KCC1G_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KCC1G_HUMAN
• UniProt AC: Q96NX5
• Protein Name: Calcium/calmodulin-dependent protein kinase type 1G
• Gene Name: CAMK1G
• Organism: Homo sapiens (Human).
• Sequence Length: 476
• Subcellular Localization: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.
• Protein Description: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1 (By similarity)..
• Protein Sequence: MGRKEEDDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPGVRPEVENRPPETQASETSRPSSPEITITEAPVLDHSVALPALTQLPCQHGRRPTAPGGRSLNCLVNGSLHISSSLVPMHQGSLAAGPCGCCSSCLNIGSKGKSSYCSEPTLLKKANKKQNFKSEVMVPVKASGSSHCRAGQTGVCLIM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	KEEDDCSSWKKQTTN CCCCCCHHHHHHCHH	49.61	29759185
56	Acetylation	FALKCIKKSPAFRDS HHHHHHHCCCCCCCC	41.58	7338969
57	Phosphorylation	ALKCIKKSPAFRDSS HHHHHHCCCCCCCCC	19.23	24719451
73	Acetylation	ENEIAVLKKIKHENI HHHHHHHHHCCCCCC	45.94	7338979
73	Ubiquitination	ENEIAVLKKIKHENI HHHHHHHHHCCCCCC	45.94	30230243
168	Phosphorylation	MITDFGLSKMEQNGI EEEECCHHHHHHCCC	30.27	21815630
433	Phosphorylation	GSKGKSSYCSEPTLL CCCCCCCCCCHHHHH	13.69	29759185

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KCC1G_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KCC1G_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KCC1G_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CDC45_HUMAN	CDC45	physical	21988832
ZBT44_HUMAN	ZBTB44	physical	28514442
RFWD3_HUMAN	RFWD3	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.