K0513_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: K0513_HUMAN
• UniProt AC: O60268
• Protein Name: Uncharacterized protein KIAA0513
• Gene Name: KIAA0513
• Organism: Homo sapiens (Human).
• Sequence Length: 411
• Subcellular Localization: Cytoplasm .
• Protein Sequence: METPEVPVGSLIDFGPEAPTSSPLEAPPPVLQDGDGSLGDGASESETTESADSENDMGESPSHPSWDQDRRSSSNESFSSNQSTESTQDEETLALRDFMRGYVEKIFSGGEDLDQEEKAKFGEYCSSENGKGREWFARYVSAQRCNSKCVSEATFYRLVQSFAVVLFECHQMDDFGPAKNLMTMCFTYYHIGKPQLLPPESREKPAGSIDSYLKSANSWLAEKKDIAERLLKNTSARTENVKGFFGGLETKLKGPLARRNEEDENKPQEKRPRAVTAYSPEDEKKGEKIYLYTHLKQQPIWHTLRFWNAAFFDAVHCERTKRSPTTRGDAGEEEEKREKWCHMTQEERDDSLRFNENITFGQLGTFTHNMLAFGLNKKLCNDFLKKQAVIGNLDEEQYKLLSDHIEQMATE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
72	Phosphorylation	SWDQDRRSSSNESFS CCCCCCCCCCCCCCC	38.73	30278072
73	Phosphorylation	WDQDRRSSSNESFSS CCCCCCCCCCCCCCC	35.06	25849741
74	Phosphorylation	DQDRRSSSNESFSSN CCCCCCCCCCCCCCC	45.95	30278072
77	Phosphorylation	RRSSSNESFSSNQST CCCCCCCCCCCCCCC	34.38	26699800
79	Phosphorylation	SSSNESFSSNQSTES CCCCCCCCCCCCCCC	37.34	28857561
80	Phosphorylation	SSNESFSSNQSTEST CCCCCCCCCCCCCCC	36.56	26657352
83	Phosphorylation	ESFSSNQSTESTQDE CCCCCCCCCCCCCCH	38.09	23186163
84	Phosphorylation	SFSSNQSTESTQDEE CCCCCCCCCCCCCHH	24.96	23186163
86	Phosphorylation	SSNQSTESTQDEETL CCCCCCCCCCCHHHH	31.30	28270605
87	Phosphorylation	SNQSTESTQDEETLA CCCCCCCCCCHHHHH	33.53	28270605
118	Ubiquitination	EDLDQEEKAKFGEYC CCCCHHHHHHHHHHC	57.00	30230243
204	Acetylation	LPPESREKPAGSIDS CCHHHCCCCCCCHHH	38.77	7673917
214	Acetylation	GSIDSYLKSANSWLA CCHHHHHHHHHHHHH	39.01	7679123
218	Phosphorylation	SYLKSANSWLAEKKD HHHHHHHHHHHHHHH	24.15	28348404
223	Acetylation	ANSWLAEKKDIAERL HHHHHHHHHHHHHHH	50.57	7673927
251	Acetylation	FFGGLETKLKGPLAR HHHCHHHHHCCCHHH	38.53	7340065
253	Acetylation	GGLETKLKGPLARRN HCHHHHHCCCHHHCC	61.10	7340075
276	Phosphorylation	EKRPRAVTAYSPEDE CCCCCCEEECCHHHH	20.92	28152594
278	Phosphorylation	RPRAVTAYSPEDEKK CCCCEEECCHHHHHC	18.52	28152594
279	Phosphorylation	PRAVTAYSPEDEKKG CCCEEECCHHHHHCC	21.25	25159151
290	Phosphorylation	EKKGEKIYLYTHLKQ HHCCCEEEEEEEHHC	12.53	27642862
292	Phosphorylation	KGEKIYLYTHLKQQP CCCEEEEEEEHHCCC	3.83	27642862
293	Phosphorylation	GEKIYLYTHLKQQPI CCEEEEEEEHHCCCH	20.38	27251275
303	Phosphorylation	KQQPIWHTLRFWNAA HCCCHHHHHHHHHHH	12.48	24719451
320	Phosphorylation	DAVHCERTKRSPTTR HHHHCCCCCCCCCCC	14.44	24706070
323	Phosphorylation	HCERTKRSPTTRGDA HCCCCCCCCCCCCCC	28.31	26699800
326	Phosphorylation	RTKRSPTTRGDAGEE CCCCCCCCCCCCCCH	35.72	28972365

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of K0513_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of K0513_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of K0513_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.