| UniProt ID | ITLN2_HUMAN | |
|---|---|---|
| UniProt AC | Q8WWU7 | |
| Protein Name | Intelectin-2 | |
| Gene Name | ITLN2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 325 | |
| Subcellular Localization | Secreted . | |
| Protein Description | May play a role in the defense system against pathogens.. | |
| Protein Sequence | MLSMLRTMTRLCFLLFFSVATSGCSAAAASSLEMLSREFETCAFSFSSLPRSCKEIKERCHSAGDGLYFLRTKNGVVYQTFCDMTSGGGGWTLVASVHENDMRGKCTVGDRWSSQQGNKADYPEGDGNWANYNTFGSAEAATSDDYKNPGYYDIQAKDLGIWHVPNKSPMQHWRNSALLRYRTNTGFLQRLGHNLFGIYQKYPVKYRSGKCWNDNGPAIPVVYDFGDAKKTASYYSPYGQREFVAGFVQFRVFNNERAANALCAGIKVTGCNTEHHCIGGGGFFPQGKPRQCGDFSAFDWDGYGTHVKSSCSREITEAAVLLFYR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 18 (in isoform 2) | Phosphorylation | - | 11.96 | 22210691 | |
| 31 | Phosphorylation | CSAAAASSLEMLSRE CCHHHHHHHHHHHHH | 24.50 | - | |
| 36 | Phosphorylation | ASSLEMLSREFETCA HHHHHHHHHHHHHHH | 28.58 | - | |
| 47 | Phosphorylation | ETCAFSFSSLPRSCK HHHHCHHHCCCHHHH | 29.75 | 29262532 | |
| 48 | Phosphorylation | TCAFSFSSLPRSCKE HHHCHHHCCCHHHHH | 40.14 | 24719451 | |
| 181 | Phosphorylation | RNSALLRYRTNTGFL HHHHHHHHHCCHHHH | 23.04 | 28270605 | |
| 183 | Phosphorylation | SALLRYRTNTGFLQR HHHHHHHCCHHHHHH | 28.35 | 28270605 | |
| 185 | Phosphorylation | LLRYRTNTGFLQRLG HHHHHCCHHHHHHHC | 28.79 | 28270605 | |
| 199 | Phosphorylation | GHNLFGIYQKYPVKY CCCCCCCCCCCCCEE | 10.18 | - | |
| 201 | "N6,N6-dimethyllysine" | NLFGIYQKYPVKYRS CCCCCCCCCCCEECC | 34.25 | - | |
| 201 | Methylation | NLFGIYQKYPVKYRS CCCCCCCCCCCEECC | 34.25 | - | |
| 267 | Acetylation | NALCAGIKVTGCNTE HHEEEEEEEEECCCC | 32.59 | 18530673 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ITLN2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ITLN2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ITLN2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CO4A2_HUMAN | COL4A2 | physical | 26186194 | |
| NUCG_HUMAN | ENDOG | physical | 26186194 | |
| NUCG_HUMAN | ENDOG | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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