dbPTM

ITBP2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ITBP2_MOUSE
UniProt AC	Q9R000
Protein Name	Integrin beta-1-binding protein 2
Gene Name	Itgb1bp2
Organism	Mus musculus (Mouse).
Sequence Length	350
Subcellular Localization
Protein Description	May play a role during maturation and/or organization of muscles cells..
Protein Sequence	MSLLCYNKGCGQHFDPNTNLPDSCRYHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTVGLHCAEKLPEVPPQPEGPATSSLQEQKPLNTIPKSAETLFRERPKSEMPPKLLPLLISQALGVALEQKELDQEPGAGLDNSLIWTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWAKQLPASCRHDWHQTDSVVVLTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVSLMPSRVEISLVKADPGSWAQLEHPDSLAEKARAGVLLEMDEEESEDSDDDLSWTEEEDEEEEEAMGE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	RKRTVDFSEFLNIKG CCCCCCHHHHHCCCC	23.99	21659604
119	Phosphorylation	KLLPLLISQALGVAL HHHHHHHHHHHHHHH	14.90	-
192	Phosphorylation	WSCCGIQTLDFGAFL CCCCCEEEECCHHHH	26.78	28576409
213	Ubiquitination	VGRHDWAKQLPASCR ECCCHHHHHCCHHHC	48.38	-
313	Ubiquitination	HPDSLAEKARAGVLL CHHHHHHHHHHCEEE	37.25	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ITBP2_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ITBP2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ITBP2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PPP5_HUMAN	PPP5C	physical	23184943
SGT1_HUMAN	SUGT1	physical	23184943
CHRD1_MOUSE	Chordc1	physical	23184943
ITBP2_MOUSE	Itgb1bp2	physical	23184943
HS90A_MOUSE	Hsp90aa1	physical	23184943
HS90B_MOUSE	Hsp90ab1	physical	18474241
SGT1_MOUSE	Sugt1	physical	18474241

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ITBP2_MOUSE

Related Literatures of Post-Translational Modification