ISY1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ISY1_SCHPO
• UniProt AC: O74370
• Protein Name: Pre-mRNA-splicing factor cwf12
• Gene Name: cwf12
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 217
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Involved in mRNA splicing and cell cycle control..
• Protein Sequence: MSSAKYVVGSKPTEKRPKDIKSIKSVPICEKHRASVVKDISRKISRIQSATLPEYQIRDLNDAINRLMREKHEWEVQIRDLGGINYLYNKAKLFEDEGEQISDIDDYRYYGRARELPGVKELFEADMSFIPERQRKQEMQKRRLDAWYFGYIPPAQESLLEDFEAKIEEQQHKHLENLGDEVEQDWKPLVIEQIPTRDDVEAILLERRKNALLSRIS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
41	Phosphorylation	ASVVKDISRKISRIQ HHHHHHHHHHHHHHH	37.34	25720772
102	Phosphorylation	EDEGEQISDIDDYRY CCCCCCCCCCCCHHC	28.36	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ISY1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ISY1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ISY1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
INV1_SCHPO	inv1	genetic	22681890
YIV5_SCHPO	SPAC144.05	genetic	22681890
RNH2A_SCHPO	rnh201	genetic	22681890
YBPD_SCHPO	SPBC16H5.13	genetic	22681890
YG42_SCHPO	rrp2	genetic	22681890
YH73_SCHPO	SPBC16G5.03	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.