INSL2_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: INSL2_DROME
• UniProt AC: Q9VT51
• Protein Name: Probable insulin-like peptide 2
• Gene Name: Ilp2
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 137
• Subcellular Localization: Secreted .
• Protein Description: Plays a role in regulating body size by increasing cell size and cell number of individual organs. Probably mediates its growth effects by acting as a ligand for the insulin receptor and transducing a signal via the Chico/PI3K/Akt(PKB) pathway..
• Protein Sequence: MSKPLSFISMVAVILLASSTVKLAQGTLCSEKLNEVLSMVCEEYNPVIPHKRAMPGADSDLDALNPLQFVQEFEEEDNSISEPLRSALFPGSYLGGVLNSLAEVRRRTRQRQGIVERCCKKSCDMKALREYCSVVRN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of INSL2_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of INSL2_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of INSL2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of INSL2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IMPL2_DROME	ImpL2	genetic	18412985
IDE_DROME	Ide	genetic	20493190
INSR_DROME	InR	genetic	11250149
IMPL2_DROME	ImpL2	physical	23307869

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.