HYI_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HYI_DROME
• UniProt AC: P36951
• Protein Name: Putative hydroxypyruvate isomerase
• Gene Name: Gip
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 264
• Protein Description: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde)..
• Protein Sequence: MALKFAANLNFLFTERATSIAERIRLAHQNGFRAVEIPYPEGETSDVVSAVKETGVVVSLVNLAFDKSDDQLRFGSTSVPGSEKLFRSQLDATIDFARQVNCGKIHLTAGLFKGGQESDYTKTYTANLKIAADSLRASKMIGVIEPINKYAVPGYYMNSYSKAAGILADVAADNIQLLADLYHLQHLHGNVSKTLEEYKALIGHFQIAQVPHRHEPDVSGELDYGFVFKALQEFGYDGWIGCEYKPKTTTVEGLGWVSKLGYTL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
84	Ubiquitination	TSVPGSEKLFRSQLD CCCCCCHHHHHHHHH	55.40	31113955

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HYI_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HYI_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HYI_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SINA_DROME	sina	physical	14605208

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.