dbPTM

HXK3_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HXK3_ARATH
UniProt AC	Q9LPS1
Protein Name	Hexokinase-3
Gene Name	At1g50460
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	498
Subcellular Localization	Mitochondrion outer membrane Single-pass membrane protein .
Protein Description	Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity)..
Protein Sequence	MGKVAVAFAAVAVVAACSVAAVMVGRRMKSRRKWRTVVEILKELEDDCDTPVGRLRQVVDAMAVEMHAGLASEGGSKLKMLLTFVDDLPTGREKGTYYALHLGGTYFRILRVLLGDQRSYLDVQDVERHPIPSHLMNSTSEVLFNFLAFSLERFIEKEENGSDSQGVRRELAFTFSFPVKHTSISSGVLIKWTKGFEISEMVGQDIAECLQGALNRRGLDMHVAALVNDTVGALSLGYYHDPDTVVAVVFGTGSNACYLERTDAIIKCQGLLTTSGSMVVNMEWGNFWSSHLPRTSYDIDLDAESSNANDMGFEKMISGMYLGDIVRRVILRMSEDSDIFGPISPVLSEPYVLRTNSVSAIHEDDTPELQEVARILKDIGVSDVPLKVRKLVVKICDVVTRRAGRLAAAGIAGILKKIGRDGSGGITSGRSRSEIQMQKRTVVAVEGGLYMNYTMFREYMEEALVEILGEEVSQYVVVKAMEDGSSIGSALLVASLQS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
433	Phosphorylation	ITSGRSRSEIQMQKR CCCCCCHHHHHCCEE	40.05	25561503
450	Phosphorylation	VAVEGGLYMNYTMFR EEEECCCCCCHHHHH	6.13	23172892
453	Phosphorylation	EGGLYMNYTMFREYM ECCCCCCHHHHHHHH	5.31	23172892
454	Phosphorylation	GGLYMNYTMFREYME CCCCCCHHHHHHHHH	12.58	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HXK3_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HXK3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HXK3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HXK1_ARATH	HXK1	physical	22366209
MD37C_ARATH	HSP70	physical	24942879
MD37E_ARATH	HSC70-1	physical	24942879

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HXK3_ARATH

Related Literatures of Post-Translational Modification