HPCL4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HPCL4_HUMAN
• UniProt AC: Q9UM19
• Protein Name: Hippocalcin-like protein 4
• Gene Name: HPCAL4
• Organism: Homo sapiens (Human).
• Sequence Length: 191
• Protein Description: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation..
• Protein Sequence: MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPSIVLLLQCDMQK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGKTNSKLA ------CCCCCCCCC	45.56	-
40	Phosphorylation	GFLKDCPSGILNLEE HHHHHCCCCCCCHHH	44.81	-
52	Phosphorylation	LEEFQQLYIKFFPYG HHHHHHHHHHHCCCC	9.57	-
74	Acetylation	HAFRTFDKNGDGTID HHHHHCCCCCCCEEE	59.65	14509389

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HPCL4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HPCL4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HPCL4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DTX2_HUMAN	DTX2	physical	16189514
TTC12_HUMAN	TTC12	physical	25416956
DTX2_HUMAN	DTX2	physical	25416956
F131C_HUMAN	FAM131C	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.