HF101_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HF101_ARATH
• UniProt AC: Q6STH5
• Protein Name: Fe-S cluster assembly factor HCF101, chloroplastic
• Gene Name: HCF101
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 532
• Subcellular Localization: Plastid, chloroplast stroma .
• Protein Description: Required for photosystem I (PSI) biosynthesis and assembly. May serve as a chloroplast scaffold protein that specifically assembles iron-sulfur (4Fe-4S) clusters and transfers them to the chloroplast PSI and ferredoxin-thioredoxin (FTR) complexes. Can assemble a 4Fe-4S cluster and transfer it to apoproteins in yeast cells. Probably not required for assembly or stability of plastidic 2Fe-2S clusters..
• Protein Sequence: MPLLHPQSLRHPSFEIQTQRRSNSTTRLLLSHKFLHSQASIISISRTRILKRVSQNLSVAKAASAQASSSVGESVAQTSEKDVLKALSQIIDPDFGTDIVSCGFVKDLGINEALGEVSFRLELTTPACPVKDMFENKANEVVAALPWVKKVNVTMSAQPAKPIFAGQLPFGLSRISNIIAVSSCKGGVGKSTVAVNLAYTLAGMGARVGIFDADVYGPSLPTMVNPESRILEMNPEKKTIIPTEYMGVKLVSFGFAGQGRAIMRGPMVSGVINQLLTTTEWGELDYLVIDMPPGTGDIQLTLCQVAPLTAAVIVTTPQKLAFIDVAKGVRMFSKLKVPCVAVVENMCHFDADGKRYYPFGKGSGSEVVKQFGIPHLFDLPIRPTLSASGDSGTPEVVSDPLSDVARTFQDLGVCVVQQCAKIRQQVSTAVTYDKYLKAIRVKVPNSDEEFLLHPATVRRNDRSAQSVDEWTGEQKVLYGDVAEDIEPEDIRPMGNYAVSITWPDGFSQIAPYDQLEEIERLVDVPPLSPVEV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
62	Acetylation	QNLSVAKAASAQASS HHHHHHHHHHHHCCC		22223895
191	Phosphorylation	CKGGVGKSTVAVNLA CCCCCCHHHHHHHHH		25368622
192	Phosphorylation	KGGVGKSTVAVNLAY CCCCCHHHHHHHHHH		25368622
199	Phosphorylation	TVAVNLAYTLAGMGA HHHHHHHHHHHHCCC		25368622
200	Phosphorylation	VAVNLAYTLAGMGAR HHHHHHHHHHHCCCE		25368622
216	Phosphorylation	GIFDADVYGPSLPTM EEEECCCCCCCCCCC		25368622
219	Phosphorylation	DADVYGPSLPTMVNP ECCCCCCCCCCCCCH		25368622
222	Phosphorylation	VYGPSLPTMVNPESR CCCCCCCCCCCHHHH		25368622
228	Phosphorylation	PTMVNPESRILEMNP CCCCCHHHHHCCCCC		25368622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HF101_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HF101_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HF101_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUMO3_ARATH	SUMO3	physical	20855607

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.