H1BP3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: H1BP3_MOUSE
• UniProt AC: Q3TC93
• Protein Name: HCLS1-binding protein 3
• Gene Name: Hs1bp3
• Organism: Mus musculus (Mouse).
• Sequence Length: 395
• Protein Description: May be a modulator of IL-2 signaling..
• Protein Sequence: MQSPAVLRTSRQVQNAHTGLDLSVPQHQEVRGKMMSGHVEYQILVVTRLAVFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLYSCYPAASLPPLPRKVLFVGESDIRERRAMFDEILRCVSKDAQLAGSPELLEFLGTRAPGATGLATRDPSVLDDTASQPGDSDEAFDFFEQQDEVQPPTLGLSSKDVEKSLVGEEEEEEEEEEVLDPLGIMRSKKPKKRPEVAVRPKPAPRLTIFDEEVDPDAGLFSSDKKVSETRRPLETTQDSLKLFDDPDLGGAVSLGDPLLLPAASESRGPTSRPEHGDASKELFRVEEDLDLILNLGSEPKPKPQTKPKPLVPAKPALPRKPTLPASVGPSEPGSGPQKQQQIQAMDEMDILQYIRDHDTLAQDSPSLF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MQSPAVLR -------CCCCHHHH	8.86	-
3	Phosphorylation	-----MQSPAVLRTS -----CCCCHHHHCH	17.33	26824392
96	Ubiquitination	SLPPLPRKVLFVGES HCCCCCCEEEEEECH	41.15	22790023
151	Phosphorylation	GLATRDPSVLDDTAS CCCCCCHHHHCCCCC	39.33	23649490
156	Phosphorylation	DPSVLDDTASQPGDS CHHHHCCCCCCCCCC	28.07	23737553
158	Phosphorylation	SVLDDTASQPGDSDE HHHCCCCCCCCCCHH	38.71	21149613
163	Phosphorylation	TASQPGDSDEAFDFF CCCCCCCCHHHHHHH	43.17	21149613
180	Phosphorylation	QDEVQPPTLGLSSKD CCCCCCCCCCCCCHH	39.89	25293948
184	Phosphorylation	QPPTLGLSSKDVEKS CCCCCCCCCHHHHHH	33.28	25293948
185	Phosphorylation	PPTLGLSSKDVEKSL CCCCCCCCHHHHHHH	37.61	25293948
191	Phosphorylation	SSKDVEKSLVGEEEE CCHHHHHHHCCCCHH	18.12	25338131
248	Phosphorylation	DPDAGLFSSDKKVSE CCCCCCCCCCCCCCC	42.54	25338131
254	Phosphorylation	FSSDKKVSETRRPLE CCCCCCCCCCCCCCC	41.97	-
262	Phosphorylation	ETRRPLETTQDSLKL CCCCCCCCCHHHHHH	37.12	28066266
263	Phosphorylation	TRRPLETTQDSLKLF CCCCCCCCHHHHHHC	22.47	28066266
266	Phosphorylation	PLETTQDSLKLFDDP CCCCCHHHHHHCCCC	20.00	30352176
335	Succinylation	PKPQTKPKPLVPAKP CCCCCCCCCCCCCCC	53.17	23806337
335	Acetylation	PKPQTKPKPLVPAKP CCCCCCCCCCCCCCC	53.17	23806337
341	Acetylation	PKPLVPAKPALPRKP CCCCCCCCCCCCCCC	25.42	-
349	Phosphorylation	PALPRKPTLPASVGP CCCCCCCCCCCCCCC	48.70	29899451
361	Phosphorylation	VGPSEPGSGPQKQQQ CCCCCCCCCHHHHHH	59.00	25338131
391	Phosphorylation	HDTLAQDSPSLF--- CCHHHCCCCCCC---	12.33	28066266
393	Phosphorylation	TLAQDSPSLF----- HHHCCCCCCC-----	46.49	17242355

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of H1BP3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of H1BP3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of H1BP3_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HCLS1_MOUSE	Hcls1	physical	10590261

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.