GIMA6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GIMA6_HUMAN
• UniProt AC: Q6P9H5
• Protein Name: GTPase IMAP family member 6
• Gene Name: GIMAP6
• Organism: Homo sapiens (Human).
• Sequence Length: 292
• Subcellular Localization: Cytoplasm, cytosol .
• Protein Sequence: MEEEEYEQIPQENPPEELSQDPVLELSGGLREKEQKTPRRLRLILMGKTGSGKSATGNSILGRDVFESKLSTRPVTKTSQRRSREWAGKELEVIDTPNILSPQVSPEVADAICQAIVLSAPGPHAVLLVTQLGRFTDEDQQVVRRLQEVFGVGVLGHTILVFTRKEDLAGGSLEDYVRETNNQALAWLDVTLARRHCGFNNRAQGEEQEAQLRELMEKVEAIMWENEGDYYSNKAYQYTQQNFRLKELQERQVSQGQGSEDVPGEESWLEGLSQIQKESEEAHRCLLGKADL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MEEEEYEQIPQEN --CCHHHHHCCCCCC	19.20	27642862
19	Phosphorylation	ENPPEELSQDPVLEL CCCCHHHCCCCCHHH	35.50	26552605
27	Phosphorylation	QDPVLELSGGLREKE CCCCHHHCCCCHHHH	22.80	26552605
37	Phosphorylation	LREKEQKTPRRLRLI CHHHHCCCCCCEEEE	23.01	-
53	Ubiquitination	MGKTGSGKSATGNSI EECCCCCCCCCCCCC	38.32	-
59	Phosphorylation	GKSATGNSILGRDVF CCCCCCCCCCCHHHH	22.12	23401153
69	Ubiquitination	GRDVFESKLSTRPVT CHHHHCCCCCCCCCC	38.98	-
79	Phosphorylation	TRPVTKTSQRRSREW CCCCCCCCCHHCHHH	24.20	-
83	Phosphorylation	TKTSQRRSREWAGKE CCCCCHHCHHHCCCE	36.42	28634120
172	Phosphorylation	KEDLAGGSLEDYVRE HHHHCCCCHHHHHHH	27.89	24719451
176	Phosphorylation	AGGSLEDYVRETNNQ CCCCHHHHHHHHCCH	7.64	24719451
191	Phosphorylation	ALAWLDVTLARRHCG HHHHHHHHHHHHHCC	17.86	24719451
230	Phosphorylation	MWENEGDYYSNKAYQ HHCCCCCCHHCHHHH	21.46	29978859
231	Phosphorylation	WENEGDYYSNKAYQY HCCCCCCHHCHHHHH	15.54	29978859
232	Phosphorylation	ENEGDYYSNKAYQYT CCCCCCHHCHHHHHH	26.14	29978859
234	Ubiquitination	EGDYYSNKAYQYTQQ CCCCHHCHHHHHHHH	42.40	-
246	Ubiquitination	TQQNFRLKELQERQV HHHCCHHHHHHHHHH	52.72	-
254	Phosphorylation	ELQERQVSQGQGSED HHHHHHHHCCCCCCC	21.91	-
259	Phosphorylation	QVSQGQGSEDVPGEE HHHCCCCCCCCCCCH	23.80	-
277	Ubiquitination	EGLSQIQKESEEAHR HHHHHHHHHHHHHHH	65.91	-
289	Ubiquitination	AHRCLLGKADL---- HHHHHHCCCCC----	38.40	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GIMA6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GIMA6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GIMA6_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.