GGYF1_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GGYF1_DROME
• UniProt AC: Q7KQM6
• Protein Name: GIGYF family protein CG11148
• Gene Name: CG11148
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 1574
• Protein Sequence: MTDSMKFGPEWLRNMSAEPSGSPSTYNVGNAAQNNSIGGHNLGNNTAASASRNLFPEYRYGREEMLSLFDRNCLLPQILPSFKKLFVEKVQCPLALTPSSEEDINQNSLGNNSRPAWLQRSPSGFGSASRGSGRGGTVDRGRMRGKSAYHPIYQRPSGLYDESLSVISKAERTWSDRNGTGDSAATTTSTSGSGALDWNGTPSSSPRKDYSNNHRNLENWRRTRNEDGSGDGPSSSGSMSGPDIAGWRSGVVGGSTNAGFGTNSHRWGRSTSWRDEDPSVDNAASLQRSISTVATLSTDRTGNNKGSGIGAAEGVGSISHPRLSSSKISQLWTVNNAAGVDADENLPEWAIENPSKLGGSFDASGAFHGDTDLKPIKSSHNTLKTKSLDSYDDVKRPKSKDLSDPDSGNDITPETSLTKDTNTTAVQEEVESSLSPISSTTTKEVIHGDISDRIKEVADEVEKLIMDDDHKISSNQSQHQNHDGFTAALPRMADIEINVKPSVTAVHRQAPSTMPIQITPTITDVAPPSHAVVSFSDHETMQHHNMHHLPQFPMIPTPHIITPNLNELWFYRDPQANVQGPFSAVEMTEWYRAGYFNENLFVRRYSDNRFRPLGELIKFCHGNMPFTHSHLLPSPIELENIPVGQIPAPLTASLSITPHKPSPIPIALSVVEQQLQQQRDEQLKANVTATAEALRAAIKGSFGGNSIGNTSHLLTMRFQMLQDQYIQHQEYQILAELSKNECFQRLSAVEQETVVRRKVQLLGLPEYLISLNGLSNSLSVLNPVAGRQLYRAVVEHAKKDQQHIFANTEQQRSVGNLLDANNFILNAQIMIQQSQQEVGPLVSSVDCIMQGGTAADLNKPNEIPRNELDLINEYNLRMLLRGQPTSTQQQPPALTNSATENLPGVDFLTETQLLERQNLMIPIWLPPNNNKQQETDQQWAEMSNADASLWETANLNEERNEDQQLLIQKSSEACFADTEKDVKIAQLFQVQSGNVVNHTALEELDQSPQNLKGSHNQKIVKSLVSDIQQNHNEELNSHQHQVKQANKQNLNTKQNAAQSALKPINNENDRKREQTEEKKRQREERKRQQLEDDKRRALNESEEQTRQIQEEKERQQQIQAQRRKALLGNVHSLSVQNGMSGTLASAQSKKNDDAKTAEPQVSSRLPSTSVAPWSFQLQNSMRSAPGLAEIQKAERRERRADQQRHQELLDKQLRANAAAAAEANDALLKWQSTPASAPVMSLAEIQAEEARRLANDLVDRQRRRELEHHQQAPLSSAVLVTSATSNIWGNANKAWSSSAAQSLSLKTSSGTGLWDEPNPLGSNGSGTSGTSSVTAAAVLAGGLNSANKSTLQAQNKSSALFASPRNLRKSQTLPALSNPEKSNKNGPGQRPEKQKLAQTRSKGAAVSIEEKDRERKLNAKSQQSSTDQAISKVNEYENEFTSWCIKSLDNMSAKVDVPTFVAFLQDLEAPYEVKDYVRIYLGDGKDSLDFAKQFLERRSKYKSLQRAQKAHNDDMCKPAPAITPSANDYADSKNKQKKIKKNKMTKMDARILGFSVTAAEGRINVGIRDYVEGP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
149	Phosphorylation	RMRGKSAYHPIYQRP CCCCCCCCCCCCCCC		18281928
153	Phosphorylation	KSAYHPIYQRPSGLY CCCCCCCCCCCCCCC		18281928
157	Phosphorylation	HPIYQRPSGLYDESL CCCCCCCCCCCCCCH		21082442
270	Phosphorylation	NSHRWGRSTSWRDED CCCCCCCCCCCCCCC		19429919
271	Phosphorylation	SHRWGRSTSWRDEDP CCCCCCCCCCCCCCC		22668510
272	Phosphorylation	HRWGRSTSWRDEDPS CCCCCCCCCCCCCCC		19429919
279	Phosphorylation	SWRDEDPSVDNAASL CCCCCCCCCCCHHHH		29892262
289	Phosphorylation	NAASLQRSISTVATL CHHHHHHHHHHEEEE		25749252
291	Phosphorylation	ASLQRSISTVATLST HHHHHHHHHEEEECC		19060867
307	Phosphorylation	RTGNNKGSGIGAAEG CCCCCCCCCCCCCCC		19429919
387	Phosphorylation	HNTLKTKSLDSYDDV CCCCCCCCCCCCCCC		19429919
399	Phosphorylation	DDVKRPKSKDLSDPD CCCCCCCCCCCCCCC		22817900
403	Phosphorylation	RPKSKDLSDPDSGND CCCCCCCCCCCCCCC		22817900
407	Phosphorylation	KDLSDPDSGNDITPE CCCCCCCCCCCCCCC		19429919
412	Phosphorylation	PDSGNDITPETSLTK CCCCCCCCCCCCCCC		25749252
433	Phosphorylation	VQEEVESSLSPISST HHHHHHHHCCCCCCC		28490779
435	Phosphorylation	EEVESSLSPISSTTT HHHHHHCCCCCCCCC		29892262
451	Phosphorylation	EVIHGDISDRIKEVA HHHCCCHHHHHHHHH		22817900
992	Phosphorylation	AQLFQVQSGNVVNHT HHEEECCCCCCCCHH		22817900
1007	Phosphorylation	ALEELDQSPQNLKGS HHHHHHCCCCCCCCH		22817900
1022	Phosphorylation	HNQKIVKSLVSDIQQ HHHHHHHHHHHHHHH		21082442
1132	Phosphorylation	ALLGNVHSLSVQNGM HHHHCHHHHHHCCCC		21082442
1134	Phosphorylation	LGNVHSLSVQNGMSG HHCHHHHHHCCCCCC		21082442
1296	Phosphorylation	GNANKAWSSSAAQSL CCCCHHHCCHHHHHC		21082442
1357	Phosphorylation	TLQAQNKSSALFASP HHHHCCHHHCCCCCC		29892262
1363	Phosphorylation	KSSALFASPRNLRKS HHHCCCCCCCCCCCC		28490779
1370	Phosphorylation	SPRNLRKSQTLPALS CCCCCCCCCCCCCCC		19429919
1372	Phosphorylation	RNLRKSQTLPALSNP CCCCCCCCCCCCCCC		19429919
1407	Phosphorylation	RSKGAAVSIEEKDRE HHCCCCCCCCHHHHH		19429919
1425	Phosphorylation	NAKSQQSSTDQAISK CCHHCCCCHHHHHHH		27794539

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GGYF1_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GGYF1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GGYF1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SINAL_DROME	sinah	physical	14605208
GSC_DROME	Gsc	physical	14605208

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.