G6PD1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: G6PD1_ARATH
• UniProt AC: Q43727
• Protein Name: Glucose-6-phosphate 1-dehydrogenase 1, chloroplastic
• Gene Name: APG1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 576
• Subcellular Localization: Plastid, chloroplast.
• Protein Description: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division..
• Protein Sequence: MATHSMIIPSPSSSSSSLATAASPFKETLPLFSRSLTFPRKSLFSQVRLRFFAEKHSQLDTSNGCATNFASLQDSGDQLTEEHVTKGESTLSITVVGASGDLAKKKIFPALFALFYEGCLPQDFSVFGYARTKLTHEELRDMISSTLTCRIDQREKCGDKMEQFLKRCFYHSGQYNSEEDFAELNKKLKEKEAGKISNRLYYLSIPPNIFVDVVRCASLRASSENGWTRVIVEKPFGRDSESSGELTRCLKQYLTEEQIFRIDHYLGKELVENLSVLRFSNLVFEPLWSRNYIRNVQLIFSEDFGTEGRGGYFDQYGIIRDIMQNHLLQILALFAMETPVSLDAEDIRSEKVKVLRSMKPLRLEDVVVGQYKGHNKGGKTYPGYTDDPTVPNHSLTPTFAAAAMFINNARWDGVPFLMKAGKALHTRGAEIRVQFRHVPGNLYKKSFATNLDNATNELVIRVQPDEGIYLRINNKVPGLGMRLDRSDLNLLYRSRYPREIPDAYERLLLDAIEGERRLFIRSDELDAAWDLFTPALKELEEKKIIPELYPYGSRGPVGAHYLASKYNVRWGDLGEA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
92	Phosphorylation	TKGESTLSITVVGAS CCCCCEEEEEEEECC	19.12	28011693
94	Phosphorylation	GESTLSITVVGASGD CCCEEEEEEEECCCH	13.03	28011693
522	Phosphorylation	ERRLFIRSDELDAAW CCEEEEEHHHHHHHH	30.53	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of G6PD1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of G6PD1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of G6PD1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
G6PD4_ARATH	G6PD4	physical	21309870
TRXM2_ARATH	ATHM2	physical	21309870

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.