FTSH5_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FTSH5_ARATH
• UniProt AC: Q9FH02
• Protein Name: ATP-dependent zinc metalloprotease FTSH 5, chloroplastic
• Gene Name: FTSH5
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 704
• Subcellular Localization: Plastid, chloroplast thylakoid membrane ; Single-pass membrane protein ; Stromal side .
• Protein Description: Part of a complex that function as an ATP-dependent zinc metallopeptidase. Involved in the thylakoid formation and in the removal of damaged D1 in the photosystem II, preventing cell death under high-intensity light conditions. Not involved in the degradation of the light-harvesting complex of photosystem II (LHC II) or in thermotolerance..
• Protein Sequence: MATTSSNPLLLSSNFLGSQIIISAPTPKTTTKSLPFSVISRKRYQISQSEKLMKSLPSQAALAALLFSSSSPQALAVNEPVQPPAPTITAEAQSPNLSTFGQNVLMTAPNPQAQSSDLPDGTQWRYSEFLNAVKKGKVERVKFSKDGSVLQLTAVDNRRATVIVPNDPDLIDILAMNGVDISVSEGEGGNGLFDFIGNLLFPLLAFGGLFYLFRGGQGGAGGPGGLGGPMDFGRSKSKFQEVPETGVTFGDVAGADQAKLELQEVVDFLKNPDKYTALGAKIPKGCLLVGPPGTGKTLLARAVAGEAGVPFFSCAASEFVELFVGVGASRVRDLFEKAKSKAPCIVFIDEIDAVGRQRGAGMGGGNDEREQTINQLLTEMDGFSGNSGVIVLAATNRPDVLDSALLRPGRFDRQVTVDRPDVAGRVQILKVHSRGKAIGKDVDYEKVARRTPGFTGADLQNLMNEAAILAARRELKEISKDEISDALERIIAGPEKKNAVVSEEKKRLVAYHEAGHALVGALMPEYDPVAKISIIPRGQAGGLTFFAPSEERLESGLYSRSYLENQMAVALGGRVAEEVIFGDENVTTGASNDFMQVSRVARQMVERFGFSKKIGQVAVGGAGGNPFLGQSMSSQKDYSMATADVVDAEVRELVEKAYVRAKEIITTQIDILHKLAQLLIEKETVDGEEFMSLFIDGQAELYVS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
235	Phosphorylation	GPMDFGRSKSKFQEV CCCCCCCCHHHCEEC	41.48	19376835
237	Phosphorylation	MDFGRSKSKFQEVPE CCCCCCHHHCEECCC	39.69	19376835
245	Phosphorylation	KFQEVPETGVTFGDV HCEECCCCCCCHHHC	30.77	19376835
248	Phosphorylation	EVPETGVTFGDVAGA ECCCCCCCHHHCCCH	24.20	19376835
416	Phosphorylation	GRFDRQVTVDRPDVA CCCCCEEEECCCCCC	14.35	29654922
639	Phosphorylation	MSSQKDYSMATADVV CCCCCCHHHHHHHHH	16.45	29797451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FTSH5_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FTSH5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FTSH5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FTSH2_ARATH	VAR2	physical	14630971

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.