FSD1L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FSD1L_HUMAN
• UniProt AC: Q9BXM9
• Protein Name: FSD1-like protein
• Gene Name: FSD1L
• Organism: Homo sapiens (Human).
• Sequence Length: 530
• Protein Sequence: MDSQKYCFKENENVTVDKACFLISNITIGPESINLQQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSENGMTGSASSLNNVVTQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1 (in isoform 3)	Acetylation	-	11.46	22814378
1 (in isoform 2)	Acetylation	-	11.46	22814378
45	Phosphorylation	EALQRIISTLANKND HHHHHHHHHHHCCCH	18.26	25627689
46	Phosphorylation	ALQRIISTLANKNDE HHHHHHHHHHCCCHH	21.34	25159151
85	Phosphorylation	ELDEEFDSLYSILDE HHHHHHHHHHHHHHH	34.23	25338102
109	Phosphorylation	KQEQARKSQELQSQI HHHHHHHHHHHHHHH	24.27	25693802
114	Phosphorylation	RKSQELQSQISQCNN HHHHHHHHHHHHHHH	41.95	30622161
117	Phosphorylation	QELQSQISQCNNALE HHHHHHHHHHHHHHH	22.50	30622161
140	Ubiquitination	ATRSLDIKEPEEFSK HHHHCCCCCHHHHHH	67.87	-
157	Phosphorylation	RQIKDRVTMASAFRL HHHHHHHHHHHHHHH	14.12	26074081
160	Phosphorylation	KDRVTMASAFRLSLK HHHHHHHHHHHHHCC	19.67	24719451
165	Phosphorylation	MASAFRLSLKPKVSD HHHHHHHHCCCCCCC	30.05	26074081
171	Phosphorylation	LSLKPKVSDNMTHLM HHCCCCCCCCCEEEE	29.41	26074081
175	Phosphorylation	PKVSDNMTHLMVDFS CCCCCCCEEEEECCH	20.36	26074081
182	Phosphorylation	THLMVDFSQERQMLQ EEEEECCHHHHHHHH	27.03	26074081
268	Acetylation	EYTLSGLKFDSKYMN EEEECCEECCCCCCC	51.13	7704317
268	Ubiquitination	EYTLSGLKFDSKYMN EEEECCEECCCCCCC	51.13	-
272	Ubiquitination	SGLKFDSKYMNFRVR CCEECCCCCCCEEEC	50.81	-
273	Phosphorylation	GLKFDSKYMNFRVRA CEECCCCCCCEEECC	10.97	24275569
289	Phosphorylation	NKAVAGEYSDPVTLE CHHHCCCCCCCEEEE	19.91	24275569
290	Phosphorylation	KAVAGEYSDPVTLET HHHCCCCCCCEEEEE	31.01	24275569
298	Ubiquitination	DPVTLETKALNFNLD CCEEEEEEEEEEECC	41.31	-
307	Phosphorylation	LNFNLDNSSSHLNLK EEEECCCCCCCCCEE	32.65	30622161
308	Phosphorylation	NFNLDNSSSHLNLKV EEECCCCCCCCCEEE	28.21	30622161
309	Phosphorylation	FNLDNSSSHLNLKVE EECCCCCCCCCEEEE	31.64	30622161
343	Phosphorylation	GKENKGRSGTPSPKR CCCCCCCCCCCCCCC	56.54	24719451
345	Phosphorylation	ENKGRSGTPSPKRTS CCCCCCCCCCCCCCC	23.11	28985074
347	Phosphorylation	KGRSGTPSPKRTSVG CCCCCCCCCCCCCCC	42.78	28985074
351	Phosphorylation	GTPSPKRTSVGSRPP CCCCCCCCCCCCCCC	33.61	19664995
352	Phosphorylation	TPSPKRTSVGSRPPA CCCCCCCCCCCCCCC	28.63	26074081
355	Phosphorylation	PKRTSVGSRPPAVRG CCCCCCCCCCCCCCC	39.18	26074081
372	Phosphorylation	DRFTGESYTVLGDTA CCCCCCEEEEEECEE	9.14	22817900
378	Phosphorylation	SYTVLGDTAIESGQH EEEEEECEEECCCCE	27.95	22817900
386	Phosphorylation	AIESGQHYWEVKAQK EECCCCEEEEEEEEC	8.72	22817900
496	Phosphorylation	MVWCGGLSLSTGMQV EEEECCEECCCCCCC	24.45	21712546
498	Phosphorylation	WCGGLSLSTGMQVPS EECCEECCCCCCCCH	21.38	21712546
499	Phosphorylation	CGGLSLSTGMQVPSA ECCEECCCCCCCCHH	41.80	21712546
513	Phosphorylation	AVRTLQKSENGMTGS HHHHHHCCCCCCCCC	24.27	30108239
518	Phosphorylation	QKSENGMTGSASSLN HCCCCCCCCCHHHCC	29.41	30108239
520	Phosphorylation	SENGMTGSASSLNNV CCCCCCCCHHHCCCC	18.79	22617229
522	Phosphorylation	NGMTGSASSLNNVVT CCCCCCHHHCCCCCC	36.74	30108239
523	Phosphorylation	GMTGSASSLNNVVTQ CCCCCHHHCCCCCCC	34.53	22617229
529	Phosphorylation	SSLNNVVTQ------ HHCCCCCCC------	25.03	23090842

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FSD1L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FSD1L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FSD1L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.