FKB1B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FKB1B_MOUSE
• UniProt AC: Q9Z2I2
• Protein Name: Peptidyl-prolyl cis-trans isomerase FKBP1B
• Gene Name: Fkbp1b
• Organism: Mus musculus (Mouse).
• Sequence Length: 108
• Subcellular Localization: Cytoplasm. Sarcoplasmic reticulum.
• Protein Description: Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)..
• Protein Sequence: MGVEIETISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGTAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLSLE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	S-nitrosocysteine	FPKKGQICVVHYTGM CCCCCCEEEEEEECC	1.69	-
23	S-nitrosylation	FPKKGQICVVHYTGM CCCCCCEEEEEEECC	1.69	21278135
36	Ubiquitination	GMLQNGKKFDSSRDR CCEECCCCCCCCCCC	56.66	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FKB1B_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FKB1B_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FKB1B_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RYR2_MOUSE	Ryr2	physical	16481613

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.