FHL3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FHL3_MOUSE
• UniProt AC: Q9R059
• Protein Name: Four and a half LIM domains protein 3
• Gene Name: Fhl3
• Organism: Mus musculus (Mouse).
• Sequence Length: 289
• Protein Sequence: MSEAFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNECYCTAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCKTPLAGQQFTSRDDDPYCVACFGELFAPKCSSCKRPITGGSGGGEGAGLGGGKYVSFEDRHWHHSCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSEAFDCAK ------CCCCCHHHC	37.32	-
95	Phosphorylation	LCNECYCTAFSSQCS CCCCCEEECCHHHCC	12.31	-
98	Phosphorylation	ECYCTAFSSQCSACG CCEEECCHHHCCCCC	19.62	-
99	Phosphorylation	CYCTAFSSQCSACGE CEEECCHHHCCCCCC	28.84	-
150	Glutathionylation	PDKGAHYCVPCYENK CCCCCCEEEECCCCC	1.66	24333276
153	Glutathionylation	GAHYCVPCYENKFAP CCCEEEECCCCCCCH	3.12	24333276
157	Ubiquitination	CVPCYENKFAPRCAR EEECCCCCCCHHHHH	30.85	22790023
157	Ubiquitination	CVPCYENKFAPRCAR EEECCCCCCCHHHHH	30.85	22790023
157	Acetylation	CVPCYENKFAPRCAR EEECCCCCCCHHHHH	30.85	23806337
167	Ubiquitination	PRCARCSKTLTQGGV HHHHHCCCEEEECCC	51.70	22790023
167	Ubiquitination	PRCARCSKTLTQGGV HHHHHCCCEEEECCC	51.70	22790023
168	Phosphorylation	RCARCSKTLTQGGVT HHHHCCCEEEECCCE	20.81	25338131
192	Ubiquitination	CLVCTGCKTPLAGQQ EEEECCCCCCCCCCC	55.30	22790023
192	Ubiquitination	CLVCTGCKTPLAGQQ EEEECCCCCCCCCCC	55.30	22790023
193	Phosphorylation	LVCTGCKTPLAGQQF EEECCCCCCCCCCCC	27.84	28542873
229	Phosphorylation	SSCKRPITGGSGGGE CCCCCCCCCCCCCCC	37.87	22942356
232	Phosphorylation	KRPITGGSGGGEGAG CCCCCCCCCCCCCCC	35.08	28464351
244	Acetylation	GAGLGGGKYVSFEDR CCCCCCCCEEECCCC	45.84	23806337

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FHL3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FHL3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FHL3_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CTBP2_MOUSE	Ctbp2	physical	16940173

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.