FEZ2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FEZ2_MOUSE
• UniProt AC: Q6TYB5
• Protein Name: Fasciculation and elongation protein zeta-2
• Gene Name: Fez2
• Organism: Mus musculus (Mouse).
• Sequence Length: 348
• Protein Description: Involved in axonal outgrowth and fasciculation..
• Protein Sequence: MAADGDWQDFYEFQEPAGSVQEQENCNASPEAGAGAHAGGDSFPALASSLEEKLSLCFRPTSEAEPPRAAVRPITECSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGMNDGLLFDASDEEELREQLDMHSIIVSCVNEEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSMSSYEERVKRLSVSELNELLEEIEAAIKQYSEELVQQLALRDELEFEKEVENSFISALIEVQNKQKEHKETAKKKKKLKSGSSQNGRSERSHMPGTYLTTVIPYEKKSGPPSVEDLQILTKILHAMKEDSEKVPSLLTDYILKVLCPT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
130	Phosphorylation	DGLLFDASDEEELRE CCCCCCCCCHHHHHH	47.61	26370283
171	Phosphorylation	IEEMMQESPDPEDDE HHHHHHHCCCCCCCC	20.08	-
190	Phosphorylation	SDRLSMLSQEIQTLK HHHHHHHHHHHHHHH	19.68	27180971
199	Phosphorylation	EIQTLKRSSMSSYEE HHHHHHHHCCCHHHH	28.89	27087446
200	Phosphorylation	IQTLKRSSMSSYEER HHHHHHHCCCHHHHH	27.07	27087446
202	Phosphorylation	TLKRSSMSSYEERVK HHHHHCCCHHHHHHH	31.54	27087446
203	Phosphorylation	LKRSSMSSYEERVKR HHHHCCCHHHHHHHH	28.11	27087446
204	Phosphorylation	KRSSMSSYEERVKRL HHHCCCHHHHHHHHC	17.95	23684622
212	Phosphorylation	EERVKRLSVSELNEL HHHHHHCCHHHHHHH	27.85	26824392
214	Phosphorylation	RVKRLSVSELNELLE HHHHCCHHHHHHHHH	32.75	26239621
271	Phosphorylation	KQKEHKETAKKKKKL HHHHHHHHHHHHHHC	48.89	22807455
332	Ubiquitination	AMKEDSEKVPSLLTD HHHHCCCCCCHHHHH	64.50	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FEZ2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FEZ2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FEZ2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NECD_MOUSE	Ndn	physical	15649943

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.