FABP7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FABP7_HUMAN
• UniProt AC: O15540
• Protein Name: Fatty acid-binding protein, brain
• Gene Name: FABP7
• Organism: Homo sapiens (Human).
• Sequence Length: 132
• Subcellular Localization: Cytoplasm.
• Protein Description: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity)..
• Protein Sequence: MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTLTFGDVVAVRHYEKA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MVEAFCATW ------CCCCEEEEE	7.95	-
8	Phosphorylation	MVEAFCATWKLTNSQ CCCCEEEEEECCCCC	25.06	28857561
12	Phosphorylation	FCATWKLTNSQNFDE EEEEEECCCCCCHHH	29.15	30622161
14	Phosphorylation	ATWKLTNSQNFDEYM EEEECCCCCCHHHHH	22.67	28857561
20	Phosphorylation	NSQNFDEYMKALGVG CCCCHHHHHHHHCCC	13.03	30622161
54	Phosphorylation	GDKVVIRTLSTFKNT CCEEEEEECCCCCCC	17.59	23312004
56	Phosphorylation	KVVIRTLSTFKNTEI EEEEEECCCCCCCEE	31.05	23312004
57	Phosphorylation	VVIRTLSTFKNTEIS EEEEECCCCCCCEEE	41.56	23312004
61	Phosphorylation	TLSTFKNTEISFQLG ECCCCCCCEEEEECC	34.97	-
83	Phosphorylation	ADDRNCKSVVSLDGD CCCCCCCEEEEECCC	29.92	28857561
86	Phosphorylation	RNCKSVVSLDGDKLV CCCCEEEEECCCEEE	20.70	28857561
117	Phosphorylation	KDGKMVMTLTFGDVV ECCCEEEEEEECCEE	15.96	24719451
119	Phosphorylation	GKMVMTLTFGDVVAV CCEEEEEEECCEEEE	19.19	-
129	Phosphorylation	DVVAVRHYEKA---- CEEEEEEEECC----	14.46	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FABP7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FABP7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FABP7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ALDR_HUMAN	AKR1B1	physical	26344197
PPIL3_HUMAN	PPIL3	physical	26344197

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.