FA71D_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FA71D_HUMAN
• UniProt AC: Q8N9W8
• Protein Name: Protein FAM71D
• Gene Name: FAM71D
• Organism: Homo sapiens (Human).
• Sequence Length: 422
• Protein Sequence: MKKNTSKTTMRINKQDALCTPHSHDPRDLQNMLDGGEYAPFVSPPMLESNFIQVNRRGESIYLHNRANWVTVGICFSSSTHKIPNVMLLAHLTPGAQKDTETLFKSLLTSPPAEKLVLTRFLPLQFVTLSVHDAENMSLKVKLVSGRAYYLQLCTSAYKQDTLFSQWVALISLLNQEKAKVSKVSEVSSLSGITNSTDITGSMDVTDVTTFTAILTPYMYAGTGPEHVRDSIDFPEFTDITDITDVTDLPENEVPEVPDVRIVTEVIEVREATEVTDSSDITNCSGVTVVFENNDLIRAKQEEKEKLKNILKPGCLQDTKSKSELKESSKHVTISNITLTFEGKRYFQTTLTPVESEANTSKEMKDKTSEEKMPDFQSTALKAEESRSLRTESNTSVLSPHIKSPSNFLKLVPHLSAPFSRE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MKKNTSKTT ------CCCCCCCCC	55.52	7933683
3	Acetylation	-----MKKNTSKTTM -----CCCCCCCCCC	65.25	7933691
6	Phosphorylation	--MKKNTSKTTMRIN --CCCCCCCCCCCCC	37.08	-
60	Phosphorylation	QVNRRGESIYLHNRA EECCCCCEEEEECCC	21.25	24719451
106	O-linked_Glycosylation	DTETLFKSLLTSPPA CHHHHHHHHHCCCCH	22.68	30379171
162	Phosphorylation	TSAYKQDTLFSQWVA HHHHHHHCHHHHHHH	27.49	24043423
165	Phosphorylation	YKQDTLFSQWVALIS HHHHCHHHHHHHHHH	26.67	24043423
312	Ubiquitination	EKLKNILKPGCLQDT HHHHHHCCCCHHCCC	35.25	29967540
320	Ubiquitination	PGCLQDTKSKSELKE CCHHCCCCCHHHHHH	65.26	29967540
321 (in isoform 2)	Phosphorylation	-	43.43	22210691
322	Ubiquitination	CLQDTKSKSELKESS HHCCCCCHHHHHHHC	49.89	29967540
338 (in isoform 2)	Phosphorylation	-	24.81	22210691
339 (in isoform 2)	Phosphorylation	-	4.59	22210691
349	Phosphorylation	EGKRYFQTTLTPVES CCEEEEEEEEECCCC	17.55	30622161
350	Phosphorylation	GKRYFQTTLTPVESE CEEEEEEEEECCCCC	20.18	30622161
352	Phosphorylation	RYFQTTLTPVESEAN EEEEEEEECCCCCCC	24.16	30622161
378	Phosphorylation	EKMPDFQSTALKAEE HHCCCHHHHHHHHHH	18.68	22210691
386	Phosphorylation	TALKAEESRSLRTES HHHHHHHHHHCCCCC	20.76	22210691
388	Phosphorylation	LKAEESRSLRTESNT HHHHHHHHCCCCCCC	31.33	30576142
399	Phosphorylation	ESNTSVLSPHIKSPS CCCCCCCCCCCCCHH	16.57	29396449
406	Phosphorylation	SPHIKSPSNFLKLVP CCCCCCHHHHHHHHH	47.51	-
416	Phosphorylation	LKLVPHLSAPFSRE- HHHHHHCCCCCCCC-	30.75	-
420	Phosphorylation	PHLSAPFSRE----- HHCCCCCCCC-----	34.15	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FA71D_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FA71D_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FA71D_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PGK2_HUMAN	PGK2	physical	28514442
TBA3C_HUMAN	TUBA3C	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.