F120C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F120C_HUMAN
• UniProt AC: Q9NX05
• Protein Name: Constitutive coactivator of PPAR-gamma-like protein 2
• Gene Name: FAM120C
• Organism: Homo sapiens (Human).
• Sequence Length: 1096
• Protein Sequence: MGVQGFQEFLEKRCPGAVVPVDLLKLARTVSRQQQQQHLHRQLPPTAALAPGAPRAARGSVPLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPPPQLPGARVLVDAGSALPRLYGGYQTDWVCGGQWNAMLGYLSALCQACAYPGGDGLELVVMFPGGLGKDRLAEWGRRCQAERQTAQLIVGHVGNKGTPPPRAWFLPPACLSHCVRLALIRFRVKVFQSLEDHHLEVVAFFRENGFHGLLAHDSEYALYNIPSYYSSHALKLSWNGKNLTTNQFLMQEVAKQLGLKRMNFPIFAALLGNHILPDEDLAAFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVSEYVSSIKDPSNLDVVGKDVFKQSQSRTEDKIERFKKAVEYYSVTTKLSSLPVGPSFLGFRNNRLGNPPLPRNQVGTISAGKPMFSHQVPQKVKYPPPFPVGPNSSLLFSSHALGESHAFSEDPMLQNSPFANWAVSYDSSASQFPNYLPSKASPPLGPDSSHSSSSDGDEPNGASSDHITEAFHHQPEWGNPNRDRGSWAQPVDTGVSEASLGDGEPHIPSLLSMSTRNHMDITIPPLPPVAPEVLRVAEHRHRRGLMYPYIYHVLTKGEIKIPVCIEDECNMELPPAALLFRSARQYVYGVLFSLAETQRKMERLAMRRRLPVEVPSVILKEWSAYKGKSPQTPELVSALTFREWTCPNLKKLWLGKAVEDKNRRMRAFLACMKSDTPSMLNPANVPTHLLLMCCVLRYMVQWPGGRILHRHELDTFLAQAVSTQLYEPDRLQELKIEKLDARGIQLAALFMSGVDTALFANDACGQPVPWEHCCPWIYFDGKLFQSKLIKAGRERVSLVELCDGQADLATKVEKMRQSILEGVNMNHPPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSMPLPPQGRSRGFAGLHPIPPQGGKLEIAGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGKEQTGRGSKGHKKGNKQGSSDGVSKSLELHQGRSRSQVNGNSGALIKEEKSDHRLPAPSQCALSRDSNECNNGNRYLPMNNREKNHLQEQKLETVAQRKED

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Ubiquitination	GFQEFLEKRCPGAVV HHHHHHHHHCCCCEE	62.54	-
25	Ubiquitination	VVPVDLLKLARTVSR EECHHHHHHHHHHCH	47.61	-
31	Phosphorylation	LKLARTVSRQQQQQH HHHHHHHCHHHHHHH	24.61	21060948
58	Methylation	PGAPRAARGSVPLQP CCCCCCCCCCCCCCC	36.61	-
60	Phosphorylation	APRAARGSVPLQPPL CCCCCCCCCCCCCCC	18.27	-
124	Phosphorylation	RVLVDAGSALPRLYG EEEEECCCCCCHHHC	28.49	24719451
204	Ubiquitination	IVGHVGNKGTPPPRA EEECCCCCCCCCCCH	59.23	-
285	Ubiquitination	LKLSWNGKNLTTNQF EEEEECCCCCCHHHH	45.64	-
369	Ubiquitination	SEYVSSIKDPSNLDV HHHHHHCCCHHHCCC	66.58	-
379	Ubiquitination	SNLDVVGKDVFKQSQ HHCCCCCHHHHHHCC	38.82	-
383	Ubiquitination	VVGKDVFKQSQSRTE CCCHHHHHHCCCCCH	49.22	-
392	Ubiquitination	SQSRTEDKIERFKKA CCCCCHHHHHHHHHH	39.99	-
398	Ubiquitination	DKIERFKKAVEYYSV HHHHHHHHHHHHHHE	55.76	-
402	Phosphorylation	RFKKAVEYYSVTTKL HHHHHHHHHHEECCH	8.40	29496907
404	Phosphorylation	KKAVEYYSVTTKLSS HHHHHHHHEECCHHH	16.46	29496907
417	Phosphorylation	SSLPVGPSFLGFRNN HHCCCCHHHCCCCCC	27.46	28857561
440	Phosphorylation	RNQVGTISAGKPMFS CCCCCEEECCCCCCC	30.70	28555341
443	Ubiquitination	VGTISAGKPMFSHQV CCEEECCCCCCCCCC	32.78	-
512	Phosphorylation	QFPNYLPSKASPPLG HCCCCCCCCCCCCCC	37.95	24719451
560	Phosphorylation	NPNRDRGSWAQPVDT CCCCCCCCCCCCCCC	21.82	24719451
567	Phosphorylation	SWAQPVDTGVSEASL CCCCCCCCCCCCCCC	39.45	27251275
570	Phosphorylation	QPVDTGVSEASLGDG CCCCCCCCCCCCCCC	28.88	24719451
573	Phosphorylation	DTGVSEASLGDGEPH CCCCCCCCCCCCCCC	28.91	28348404
667	Phosphorylation	YVYGVLFSLAETQRK HHHHHHHHHHHHHHH	23.62	29507054
671	Phosphorylation	VLFSLAETQRKMERL HHHHHHHHHHHHHHH	28.24	29507054
694	Ubiquitination	EVPSVILKEWSAYKG CCCHHHHHHHHHHCC	46.11	-
702	Ubiquitination	EWSAYKGKSPQTPEL HHHHHCCCCCCCHHH	55.61	-
725	Ubiquitination	WTCPNLKKLWLGKAV CCCCCHHHHHCCHHH	48.32	-
730	Ubiquitination	LKKLWLGKAVEDKNR HHHHHCCHHHHCHHH	47.27	-
747	Sumoylation	RAFLACMKSDTPSML HHHHHHHHCCCHHHC	45.09	17000644
747	Sumoylation	RAFLACMKSDTPSML HHHHHHHHCCCHHHC	45.09	-
772	Phosphorylation	LMCCVLRYMVQWPGG HHHHHHHHHHHCCCC	9.47	22817900
789	Phosphorylation	LHRHELDTFLAQAVS EEHHHHHHHHHHHHH	32.92	-
809	Sumoylation	PDRLQELKIEKLDAR CHHHHHHCCHHHHHH	48.33	-
809	Sumoylation	PDRLQELKIEKLDAR CHHHHHHCCHHHHHH	48.33	17000644
871	O-linked_Glycosylation	KAGRERVSLVELCDG HHCCCCEEEEHHCCC	32.68	OGP
885	Ubiquitination	GQADLATKVEKMRQS CCCHHHHHHHHHHHH	42.67	-
910	Phosphorylation	PPSALLPSPTFVPPM CCHHCCCCCCCCCCC	36.22	28348404
912	Phosphorylation	SALLPSPTFVPPMVP HHCCCCCCCCCCCCC	41.42	28348404
928	Phosphorylation	LYPVSLYSRAMGSMP CCCCHHHHHCCCCCC	20.89	24719451
941	Methylation	MPLPPQGRSRGFAGL CCCCCCCCCCCCCCC	20.24	-
943	Methylation	LPPQGRSRGFAGLHP CCCCCCCCCCCCCCC	42.77	-
977	Methylation	GSRSSRGRGSFGMQV CCCCCCCCCCCCCEE	36.15	-
979	Phosphorylation	RSSRGRGSFGMQVVS CCCCCCCCCCCEEEE	19.78	27251275
986	Phosphorylation	SFGMQVVSVGGPGKG CCCCEEEEECCCCCC	19.05	-
999	Phosphorylation	KGHGKEQTGRGSKGH CCCCCCCCCCCCCCC	29.91	23532336
1014	Phosphorylation	KKGNKQGSSDGVSKS CCCCCCCCCCCCCHH	23.82	22210691
1015	Phosphorylation	KGNKQGSSDGVSKSL CCCCCCCCCCCCHHH	45.25	22210691
1021	Phosphorylation	SSDGVSKSLELHQGR CCCCCCHHHHCCCCC	21.41	25159151
1029	Phosphorylation	LELHQGRSRSQVNGN HHCCCCCCHHHHCCC	43.01	24719451
1031	Phosphorylation	LHQGRSRSQVNGNSG CCCCCCHHHHCCCCC	39.46	25159151
1042	Sumoylation	GNSGALIKEEKSDHR CCCCCEEECCCCCCC	61.75	17000644
1042	Sumoylation	GNSGALIKEEKSDHR CCCCCEEECCCCCCC	61.75	-
1054	Phosphorylation	DHRLPAPSQCALSRD CCCCCCCCCCCCCCC	39.74	-
1059	Phosphorylation	APSQCALSRDSNECN CCCCCCCCCCCCCCC	18.60	-
1062	Phosphorylation	QCALSRDSNECNNGN CCCCCCCCCCCCCCC	33.16	-
1071	Phosphorylation	ECNNGNRYLPMNNRE CCCCCCCCCCCCHHH	21.11	-
1086	Ubiquitination	KNHLQEQKLETVAQR HCHHHHHHHHHHHHH	47.76	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F120C_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F120C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F120C_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BANP_HUMAN	BANP	physical	25416956
TFCP2_HUMAN	TFCP2	physical	21516116

Drug and Disease Associations

• Kegg Disease
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.