| UniProt ID | ETV2_HUMAN | |
|---|---|---|
| UniProt AC | O00321 | |
| Protein Name | ETS translocation variant 2 | |
| Gene Name | ETV2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 342 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.. | |
| Protein Sequence | MDLWNWDEASPQEVPPGNKLAGLEGAKLGFCFPDLALQGDTPTATAETCWKGTSSSLASFPQLDWGSALLHPEVPWGAEPDSQALPWSGDWTDMACTAWDSWSGASQTLGPAPLGPGPIPAAGSEGAAGQNCVPVAGEATSWSRAQAAGSNTSWDCSVGPDGDTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSPQSDRASLARCPKTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGRGAETQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 164 | Phosphorylation | SVGPDGDTYWGSGLG EECCCCCCCCCCCCC | 16.71 | - | |
| 165 | Phosphorylation | VGPDGDTYWGSGLGG ECCCCCCCCCCCCCC | 9.14 | - | |
| 168 | Phosphorylation | DGDTYWGSGLGGEPR CCCCCCCCCCCCCCC | 25.14 | - | |
| 203 | Phosphorylation | PGLHAGGTTSLKRYQ CCCCCCCCCCCHHHH | 35.02 | 28787133 | |
| 205 | Phosphorylation | LHAGGTTSLKRYQSS CCCCCCCCCHHHHCC | 3.25 | 28787133 | |
| 212 | Phosphorylation | SLKRYQSSALTVCSE CCHHHHCCCEEEECC | 16.70 | 22210691 | |
| 224 | Phosphorylation | CSEPSPQSDRASLAR ECCCCCCCCHHHHHC | 44.94 | 22210691 | |
| 228 | Phosphorylation | SPQSDRASLARCPKT CCCCCHHHHHCCCCC | 3.21 | 21406692 | |
| 292 | Phosphorylation | KRKPGMNYEKLSRGL CCCCCCCHHHHHHHH | 42.38 | 24719451 | |
| 294 | Sumoylation | KPGMNYEKLSRGLRY CCCCCHHHHHHHHHH | 2.56 | - | |
| 294 | Sumoylation | KPGMNYEKLSRGLRY CCCCCHHHHHHHHHH | 2.56 | - | |
| 294 | Ubiquitination | KPGMNYEKLSRGLRY CCCCCHHHHHHHHHH | 2.56 | - | |
| 296 | Phosphorylation | GMNYEKLSRGLRYYY CCCHHHHHHHHHHHH | 59.61 | 24719451 | |
| 322 | Ubiquitination | KYTYRFGGRVPSLAY EEEEEECCCCCCCCC | 37.24 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ETV2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ETV2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ETV2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| KDM3A_HUMAN | KDM3A | physical | 16619273 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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