ERIP6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ERIP6_HUMAN
• UniProt AC: Q7L0X2
• Protein Name: Glutamate-rich protein 6
• Gene Name: ERICH6
• Organism: Homo sapiens (Human).
• Sequence Length: 663
• Protein Sequence: MAHLRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVPSQSATSTETPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEESWLQDLSDKVQSRKKASKEKAEPECLASKLREKWVINPEESKLNILYELEFKEDFITLFEPSLRTLPSIGPPSILAYKEESSNLGINFKDEEEETSPKCEFCGSDLRAFFSNVDVSSEPKGHASCCIAFQNLIDYIYEEQIKTKPPKAELIAIDPHAAHGSEVDRLKAKEKALQRKQEQRMARHFAIISREQTHFSEDDSKRLKTISYQLSVDIPEKQIIDDIVFDFQLRNSNMSIICCDSRIACGKVVRNELLEKHYKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVNGFTCIVQEDMPTNPAILAVLDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNSITSSPFVSFKPVFLALNRYIGVRILEQDKISITFLAMGQQARISVGTKVKLPNPEEIPILRYVSGDDLLLLASLIKIRRLFHKLEGCVNFPSSQVWEKLKQPSYLSSLSLKLIALCHSSGIKQDIMKTIRNIINEEI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
229	Phosphorylation	EFKEDFITLFEPSLR EECCCCHHHCCHHHC		26074081
234	Phosphorylation	FITLFEPSLRTLPSI CHHHCCHHHCCCCCC		26074081
237	Phosphorylation	LFEPSLRTLPSIGPP HCCHHHCCCCCCCCC		26074081
240	Phosphorylation	PSLRTLPSIGPPSIL HHHCCCCCCCCCCEE		26074081
245	Phosphorylation	LPSIGPPSILAYKEE CCCCCCCCEEEEEHH		26074081
249	Phosphorylation	GPPSILAYKEESSNL CCCCEEEEEHHHCCC		26074081
283	Phosphorylation	SDLRAFFSNVDVSSE HHHHHHHCCCCCCCC		30622161
288	Phosphorylation	FFSNVDVSSEPKGHA HHCCCCCCCCCCCCH		30622161
404	Phosphorylation	FDFQLRNSNMSIICC EEEEECCCCCEEEEE		-
438	Phosphorylation	KHGSKFLTSFPDGTT HHCCEECCCCCCCCE		29116813
439	Phosphorylation	HGSKFLTSFPDGTTQ HCCEECCCCCCCCEE		29116813
444	Phosphorylation	LTSFPDGTTQIFYPS CCCCCCCCEEEEECC		29116813
557	Phosphorylation	ILEQDKISITFLAMG EEECCCEEEEEEECC		30301811
559	Phosphorylation	EQDKISITFLAMGQQ ECCCEEEEEEECCCE		30301811
570	Phosphorylation	MGQQARISVGTKVKL CCCEEEEEECCEEEC		30301811
573	Phosphorylation	QARISVGTKVKLPNP EEEEEECCEEECCCH		30301811
599	Phosphorylation	DDLLLLASLIKIRRL HHHHHHHHHHHHHHH		24719451
630	Phosphorylation	EKLKQPSYLSSLSLK HHHCCCHHHHHHHHH		22210691
633	Phosphorylation	KQPSYLSSLSLKLIA CCCHHHHHHHHHHHH		24719451
635	Phosphorylation	PSYLSSLSLKLIALC CHHHHHHHHHHHHHH		24719451
654	Phosphorylation	IKQDIMKTIRNIINE CHHHHHHHHHHHHCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ERIP6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ERIP6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ERIP6_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GLCI1_HUMAN	GLCCI1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.