ERD6_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ERD6_ARATH
• UniProt AC: O04036
• Protein Name: Sugar transporter ERD6
• Gene Name: ERD6
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 496
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: Sugar transporter..
• Protein Sequence: MERQKSMEKGLLRKSLSIRERKFPNEDAFLESGLSRKSPREVKKPQNDDGECRVTASVFLSTFVAVSGSFCTGCGVGFSSGAQAGITKDLSLSVAEYSMFGSILTLGGLIGAVFSGKVADVLGRKRTMLFCEFFCITGWLCVALAQNAMWLDCGRLLLGIGVGIFSYVIPVYIAEIAPKHVRGSFVFANQLMQNCGISLFFIIGNFIPWRLLTVVGLVPCVFHVFCLFFIPESPRWLAKLGRDKECRSSLQRLRGSDVDISREANTIRDTIDMTENGGETKMSELFQRRYAYPLIIGVGLMFLQQLCGSSGVTYYASSLFNKGGFPSAIGTSVIATIMVPKAMLATVLVDKMGRRTLLMASCSAMGLSALLLSVSYGFQSFGILPELTPIFTCIGVLGHIVSFAMGMGGLPWIIMAEIFPMNVKVSAGTLVTVTNWLFGWIITYTFNFMLEWNASGMFLIFSMVSASSIVFIYFLVPETKGRSLEEIQALLNNSVQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	GLLRKSLSIRERKFP HHHHHHHHHHHCCCC	27.04	19880383
35	Phosphorylation	AFLESGLSRKSPREV HHHHCCCCCCCCCCC	40.98	23111157
256	Phosphorylation	SLQRLRGSDVDISRE HHHHHHCCCCCHHHH	28.20	19376835
327	Phosphorylation	FNKGGFPSAIGTSVI HHCCCCCCCCCCHHH	30.20	19880383
336	Phosphorylation	IGTSVIATIMVPKAM CCCHHHHHHHCCHHH	9.85	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ERD6_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ERD6_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ERD6_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GDU2_ARATH	GDU2	physical	22737156
YSL3_ARATH	YSL3	physical	22737156

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-256, AND MASSSPECTROMETRY.
PubMed: 19376835