dbPTM

ELF6_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ELF6_ARATH
UniProt AC	Q6BDA0
Protein Name	Probable lysine-specific demethylase ELF6
Gene Name	ELF6
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	1340
Subcellular Localization	Nucleus .
Protein Description	Acts probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus..
Protein Sequence	MGNVEIPNWLKALPLAPVFRPTDTEFADPIAYISKIEKEASAFGICKIIPPLPKPSKKYVFYNLNKSLLKCPELVSDVDISKVCKEDRAVFTTRQQELGQTVKKNKGEKGKSNSQRSGVKQVWQSGGVYTLDQFEAKSKAFYKTQLGTVKELAPVVIEALFWKAALEKPIYIEYANDVPGSAFGEPEDHFRHFRQRKRRGRGFYQRKTENNDPSGKNGEKSSPEVEKAPLASTSLSSQDSSKQKNMDIVDEMEGTAGWKLSNSSWNLQMIARSPGSVTRFMPDDIPGVTSPMVYIGMLFSWFAWHVEDHELHSMNYLHTGSPKTWYAVPCDYALDFEEVIRKNSYGRNIDQLAALTQLGEKTTLVSPEMIVASGIPCCRLVQNPGEFVVTFPRSYHVGFSHGFNCGEAANFGTPQWLNVAKEAAVRRAAMNYLPMLSHQQLLYLLTMSFVSRVPRSLLPGGRSSRLRDRQREEREFLVKRAFVEDILNENKNLSVLLREPGSRLVMWDPDLLPRHSALALAAAGVAGASAVSPPAVAKKELEEGHSELQNKEKTSLLEELSLFMEKLNDVYYDDDDGLLNDFQVDTGTLPCVACGVLGFPFMSVVQPSEKALKDLSERQGETDAQEIMTLSSEKSDCEWKTSSRYIRPRIFCLEHTIELQRLLQSRGGLKFLVICHKDFQKFKAHAAIVAEEVKVPFSYDDVLLESASQEELSLIDLAIEDEEKYEHSVDWTSELGINLRYCVKVRKNSPTKKIQHALSLGGLFSDTSQMLDFTTIRWLQRKSRSKAKPSSTSSFTPCEHLEVKADGKLRDNLDSQTGKKEEKIIQYSRKKKLNPKPSAEQVQELATLAKSKDFDKTCKNFSSRSHLDSAIRSEMNSEIGDSGRVIGVSFSINPCSSSFTVGHGQEHPEITVKFGSDLDGNVTNSLSMVNGDSADLTLTSISREQHQGHSMTSNNNGSNSGSHVVASQTILVSTGDNHDGPRKLSGDYVCSDVSVRGIQEAVEMSDQEFGEPRSTVTNIEDEQQSQIVKPTQREAVFGDHEQVEGAEAVSTRENLCSEIILHTEHSSAHVGMEIPDINTASENLVVDMTHDGEPLESSDILSSSNGDEASSNGLQVLNDELSMESEVSSSENTEVIEAPNSMGEAKKKRKIESESETNDNPESSIGFIRSPCEGLRSRGKRKATCETSLKHTETSDEEKKPIAKRLKKTPKACSGSRQQEVPTTTHPNRCYLEGCKMTFESKAKLQTHKRNRCTHEGCGKKFRAHKYLVLHQRVHKDERPFECSWKGCSMTFKWQWARTEHLRLHTGERPYICKVDGCGLSFRFVSDYSRHRRKTMHYVT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of ELF6_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ELF6_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ELF6_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ELF6_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
BZR2_ARATH	BES1	physical	18467490

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ELF6_ARATH

Related Literatures of Post-Translational Modification