ELF1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ELF1_MOUSE
• UniProt AC: Q60775
• Protein Name: ETS-related transcription factor Elf-1
• Gene Name: Elf1
• Organism: Mus musculus (Mouse).
• Sequence Length: 612
• Subcellular Localization: Nucleus.
• Protein Description: Transcription factor that activates the LYN and BLK promoters..
• Protein Sequence: MAAVVQQNDLVFEFASNGMEDEQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHNGDETIETIEAAEALLNIDSPSPPVLDEKQINNNIFSSSEDDIVAPITHVSVTLDGIPEVMETQQVQETNADSPGASSPEQRKRKKGRKTKPPRPDSPTTTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEDPSSSIESSDQSLSSTTASSRNQANRSRVSSSPGIKGGAATILKPGNSKAANPKDPVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPVQAVPEEATIASTMQEEAANSSVPSIRTIQASTQVPVVVSPGNQQLHTVTVPLTTVIASIDPSSGAGSQKFILQTIPSSQPMTVLKENVMLQSQKPGSPSIVLSPTQVQQVLTSNVQSICNGAGSVASAPSFSATTPVVTFSRSSQLVAHPPGTVITSVIKAQETKTLKQEVEKKAEDDLNEDAEKSAQQPQPYVMVLSSSNGFSSQVAVKQNELLEPNSF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
110	Phosphorylation	EALLNIDSPSPPVLD HHHHCCCCCCCCCCC	24.39	-
163	Phosphorylation	VQETNADSPGASSPE CHHCCCCCCCCCCHH	23.87	22802335
167	Phosphorylation	NADSPGASSPEQRKR CCCCCCCCCHHHHHH	52.95	22802335
168	Phosphorylation	ADSPGASSPEQRKRK CCCCCCCCHHHHHHH	31.74	22802335
180	Phosphorylation	KRKKGRKTKPPRPDS HHHCCCCCCCCCCCC	47.63	28833060
187	Phosphorylation	TKPPRPDSPTTTPNI CCCCCCCCCCCCCCE	27.16	26824392
189	Phosphorylation	PPRPDSPTTTPNISV CCCCCCCCCCCCEEE	47.45	22942356
190	Phosphorylation	PRPDSPTTTPNISVK CCCCCCCCCCCEEEE	43.57	28833060
191	Phosphorylation	RPDSPTTTPNISVKK CCCCCCCCCCEEEEE	19.47	28833060
195	Phosphorylation	PTTTPNISVKKKNKD CCCCCCEEEEEECCC	34.23	28833060
329	Phosphorylation	SRNQANRSRVSSSPG HHHHHHHHHHCCCCC	36.52	30482847
332	Phosphorylation	QANRSRVSSSPGIKG HHHHHHHCCCCCCCC	24.80	28833060
333	Phosphorylation	ANRSRVSSSPGIKGG HHHHHHCCCCCCCCC	37.38	28833060
334	Phosphorylation	NRSRVSSSPGIKGGA HHHHHCCCCCCCCCC	21.46	26824392
431	Phosphorylation	TQVPVVVSPGNQQLH CCCCEEECCCCCEEE	18.58	22006019
469	Phosphorylation	FILQTIPSSQPMTVL EEEEECCCCCCEEEE	37.44	21454597
535	Phosphorylation	PVVTFSRSSQLVAHP CEEEEECCCCCEECC	22.65	25777480
536	Phosphorylation	VVTFSRSSQLVAHPP EEEEECCCCCEECCC	26.82	25777480
545	Phosphorylation	LVAHPPGTVITSVIK CEECCCCCEEEEEEE	17.95	25777480
548	Phosphorylation	HPPGTVITSVIKAQE CCCCCEEEEEEEHHH	16.77	25777480
549	Phosphorylation	PPGTVITSVIKAQET CCCCEEEEEEEHHHH	15.66	25777480
611	Phosphorylation	NELLEPNSF------ CCCCCCCCC------	42.94	30482847

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ELF1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ELF1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ELF1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DMD_MOUSE	Dmd	physical	12149647
EPHB4_MOUSE	Ephb4	physical	8954633

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.