ELAV2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ELAV2_MOUSE
• UniProt AC: Q60899
• Protein Name: ELAV-like protein 2
• Gene Name: Elavl2
• Organism: Mus musculus (Mouse).
• Sequence Length: 360
• Protein Description: Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR..
• Protein Sequence: METQLSNGPTCNNTANGPTTVNNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKSRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	Phosphorylation	TVNNNCSSPVDSGNT CCCCCCCCCCCCCCC	31.01	25338131
51	Phosphorylation	NYLPQNMTQEELKSL ECCCCCCCHHHHHHH	40.14	30635358
74	Ubiquitination	SCKLVRDKITGQSLG HCEEECCCCCCCCCC	31.44	-
91	Ubiquitination	FVNYIDPKDAEKAIN ECEECCHHHHHHHHH	66.86	-
95	Ubiquitination	IDPKDAEKAINTLNG CCHHHHHHHHHHHHC	57.18	-
113	Phosphorylation	QTKTIKVSYARPSSA EEEEEEEEEECCCCC	14.20	19737024
114	Phosphorylation	TKTIKVSYARPSSAS EEEEEEEEECCCCCC	15.04	19737024
118	Phosphorylation	KVSYARPSSASIRDA EEEEECCCCCCCCCC	32.74	28066266
119	Phosphorylation	VSYARPSSASIRDAN EEEECCCCCCCCCCC	28.81	22817900
121	Phosphorylation	YARPSSASIRDANLY EECCCCCCCCCCCEE	21.80	28066266
134	Ubiquitination	LYVSGLPKTMTQKEL EEECCCCCCCCHHHH	56.84	-
137	Phosphorylation	SGLPKTMTQKELEQL CCCCCCCCHHHHHHH	41.54	-
139	Ubiquitination	LPKTMTQKELEQLFS CCCCCCHHHHHHHHH	55.91	-
153	Phosphorylation	SQYGRIITSRILVDQ HHHHHHHHHHHHHHH	15.02	-
162	Phosphorylation	RILVDQVTGISRGVG HHHHHHHHCCCCCCC	24.14	23140645
165	Phosphorylation	VDQVTGISRGVGFIR HHHHHCCCCCCCEEE	25.07	23140645
209	Ubiquitination	FANNPSQKTNQAILS ECCCCCHHHHHHHHH	54.50	-
210	Phosphorylation	ANNPSQKTNQAILSQ CCCCCHHHHHHHHHH	25.56	24925903
216	Phosphorylation	KTNQAILSQLYQSPN HHHHHHHHHHHCCCC	16.42	24925903
219	Phosphorylation	QAILSQLYQSPNRRY HHHHHHHHCCCCCCC	10.17	24925903
221	Phosphorylation	ILSQLYQSPNRRYPG HHHHHHCCCCCCCCC	15.58	25521595
236	Dimethylation	PLAQQAQRFRLDNLL HHHHHHHHHCHHHHH	22.97	-
316	Ubiquitination	IRDFNTNKCKGFGFV EEECCCCCCCCEEEE	34.97	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ELAV2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ELAV2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ELAV2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TFE2_MOUSE	Tcf3	physical	20211142

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.