dbPTM

EFTM_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	EFTM_ARATH
UniProt AC	Q9ZT91
Protein Name	Elongation factor Tu, mitochondrial
Gene Name	TUFA
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	454
Subcellular Localization	Mitochondrion .
Protein Description	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis..
Protein Sequence	MASVVLRNPSSKRLVPFSSQIYSRCGASVTSSYSISHSIGGDDLSSSTFGTSSFWRSMATFTRNKPHVNVGTIGHVDHGKTTLTAAITKVLAEEGKAKAIAFDEIDKAPEEKKRGITIATAHVEYETAKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSGPDGPMPQTKEHILLARQVGVPSLVCFLNKVDVVDDPELLELVEMELRELLSFYKFPGDDIPIIRGSALSALQGTNDEIGRQAILKLMDAVDEYIPDPVRVLDKPFLMPIEDVFSIQGRGTVATGRIEQGVIKVGEEVEILGLREGGVPLKSTVTGVEMFKKILDNGQAGDNVGLLLRGLKREDIQRGMVIAKPGSCKTYKKFEAEIYVLTKDEGGRHTAFFSNYRPQFYLRTADITGKVELPENVKMVMPGDNVTAVFELIMPVPLETGQRFALREGGRTVGAGVVSKVMT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
82	Phosphorylation	HVDHGKTTLTAAITK EECCCHHHHHHHHHH	26.12	-
132	Phosphorylation	YETAKRHYAHVDCPG HHHHHHHCCCCCCCC	11.48	27545962
147	Sulfoxidation	HADYVKNMITGAAQM CHHHHHHHHHCCEEC	2.10	23289948
154	Sulfoxidation	MITGAAQMDGGILVV HHHCCEECCCCEEEE	4.42	23289948
168	Sulfoxidation	VSGPDGPMPQTKEHI EECCCCCCCCCHHHH	4.74	23289948
250	Sulfoxidation	RQAILKLMDAVDEYI HHHHHHHHHHHHHHC	2.73	23289948

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of EFTM_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of EFTM_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of EFTM_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
RK121_ARATH	RPL12-A	physical	23225155

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of EFTM_ARATH

Related Literatures of Post-Translational Modification