E70A1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: E70A1_ARATH
• UniProt AC: Q9LZD3
• Protein Name: Exocyst complex component EXO70A1
• Gene Name: EXO70A1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 638
• Subcellular Localization: Cytoplasm, cytosol . Cytoplasm, cytoskeleton, phragmoplast . Cell membrane . Secreted, cell wall . During cytokinesis, localizes to the nascent cell plate and later to the cell plate insertion site and along the post-cytokinetic wall.
• Protein Description: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall. Participates in polarized pectin delivery required for the polarized development of the mucilage-producing volcano cells of the seed coat. Involved in the recycling and localization of auxin efflux carriers PIN1 and PIN2, and thus in polar auxin transport regulation. Functions in vesicle trafficking in tracheary elements to regulate patterned secondary cell wall thickening..
• Protein Sequence: MAVDSRMDLLSERAVLMRASLQKSQTITDNVVSILGSFDSRLSALETAMRPTQIRTHAIRKAHENIDRTLKAAEVILSQFDLLRQAETKVLKGPHEDLESYLDAIAQLRKIIRYFMSNKSFKSSDGVLNHANSLLAKAQSKLEEEFKQLLASYSKAVEPDRLFDGLPNSLRPSSDGDGGGKPHGGHHNDDAETAAYTLPILIPSRVLPLLHDLAQQMVQAGHQQQLLQIYRDTRSFVLEESLKKLGVEKLSKEDVQRMQWEVLEAKIGNWIHFMRIAVKLLFAGERQVCDQIFRGFDSLSDQCFAEVTVSSVSMLLSFGDAIARSKRSPEKLFVLLDMYEIMRELHTEIETIFKGKACLEIRDSATGLTKRLAQTAQETFGDFEEAVEKDATKTAVLDGTVHPLTSYVINYVKFLFDYQTTLKQLFLEFGNGDDSNSQLASVTMRIMQALQNNLDGKSKQYKDPALTHLFLMNNIHYMVRSVRRSEAKDLLGDDWVQRHRRIVQQHANQYKRVAWTKILQSSSAQGLTSSGGGSLEGGNSSGVSRGLLKERFKMFNMQFDELHQRQSQWTVPDTELRESLRLAVAEVLLPAYRSFLKRFGPLVESGKNPQKYIKYTAEDLERLLGELFEGKSMNEPRR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
123	Phosphorylation	MSNKSFKSSDGVLNH HCCCCCCCCHHHHHH		25561503
124	Phosphorylation	SNKSFKSSDGVLNHA CCCCCCCCHHHHHHH		25561503
528	Phosphorylation	SSSAQGLTSSGGGSL HCCCCCCCCCCCCCC		30407730
529	Phosphorylation	SSAQGLTSSGGGSLE CCCCCCCCCCCCCCC		30407730
530	Phosphorylation	SAQGLTSSGGGSLEG CCCCCCCCCCCCCCC		30407730
534	Phosphorylation	LTSSGGGSLEGGNSS CCCCCCCCCCCCCCC		30407730
540	Phosphorylation	GSLEGGNSSGVSRGL CCCCCCCCCCCCCHH		30407730
541	Phosphorylation	SLEGGNSSGVSRGLL CCCCCCCCCCCCHHH		30407730
544	Phosphorylation	GGNSSGVSRGLLKER CCCCCCCCCHHHHHH		30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of E70A1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of E70A1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of E70A1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SEC3A_ARATH	SEC3A	physical	18492870
EX84B_ARATH	EXO84B	physical	18492870

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.