SEC3A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SEC3A_ARATH
• UniProt AC: Q9SX85
• Protein Name: Exocyst complex component SEC3A {ECO:0000303|PubMed:19895414}
• Gene Name: SEC3A {ECO:0000303|PubMed:19895414}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 887
• Subcellular Localization: Cytoplasm, cytosol . Cell membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton, phragmoplast . Secreted, exosome . In interphase, SEC3A localizes to the cytoplasm and plasma membrane, where it forms immobile, punctate structures. Localize
• Protein Description: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall..
• Protein Sequence: MAKSSADDEELRRACEAAIEGTKQSIVMSIRVAKSRGVWGKSGKLGRQMAKPRVLALSVKSKGPRKKAFLRVMKYSSGGVLEPAKMYKLKHLSKVEVITNDPSGCTFTLGFDNLRSQSVAPPQWTMRNTDDRNRLLVCILNICKDVLGRLPKVVGIDIVEMALWAKDNTPVVTTQRSTEDGEPVAESVTESDLKVTVEKELVSQAEEEDMEALLGTYVMGIGEAEAFSERLKRELQALEAANVHAILESEPLVDEVLNGLEAATNIVDDMDEWLGIFNIKLRHMREDIESIETRNNKLEMQSVNNKALIEELDKVIERLRVPSEYAASLTGGSFDEADMLQNIEACEWLAKALRGLEVPNLDPIYANMRAVKEKRAELEKLKATFVRRASEFLRNYFASLVDFMVSDKSYFSQRGQLKRPDHADLRYKCRTYARLLQHLKGLDKNCLGPLRKAYCSSLNLLLRREAREFANELRASTKVSRNPTVWLEGSTGSSQNANTDTSAVSDAYAKMLTIFIPLLVDESSFFAHFMCFEVPALAPPGGAGNDKKSQSNNDDGNDDDDLGIMDIDETDKKPGKNSPDLTALNESLQDLLDGIQEDFYAVVDWAYKIDPLRCISMHGITERYLSGQKADAAGFVRLLLGDLESRVSMQFSRFVDEACHQIERNERNVRQMGVLPYIPRFAALATRMEQYIQGQSRDLVDQAYTKFVSIMFVTLEKIAQQDPKYADILLLENYAAFQNSLYDLANVVPTLAKFYHQASEAYEQACTRHISMIIYYQFERLFQFAKKIEDFMYTITPEEIPFQLGLSKVELRKMLKSSLSGVDKSIAAMYKKLQKNLASEELLPSLWDKCKKEFLDKYESFVQLVAKVYPSENVPGVTEMRGLLASM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MAKSSADDEEL ----CCCCCCCHHHH	22.63	19880383
5	Phosphorylation	---MAKSSADDEELR ---CCCCCCCHHHHH	34.70	19880383
177	Phosphorylation	PVVTTQRSTEDGEPV CEEEEECCCCCCCCC	26.74	25561503
178	Phosphorylation	VVTTQRSTEDGEPVA EEEEECCCCCCCCCC	40.04	25561503
300	Sulfoxidation	TRNNKLEMQSVNNKA HHCCCCCHHHHCHHH	5.36	23289948
860	Phosphorylation	EFLDKYESFVQLVAK HHHHHHHHHHHHHHH	27.85	19880383
869	Phosphorylation	VQLVAKVYPSENVPG HHHHHHHCCCCCCCC	10.59	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SEC3A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SEC3A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SEC3A_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of SEC3A_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.