DPE2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DPE2_ARATH
• UniProt AC: Q8RXD9
• Protein Name: 4-alpha-glucanotransferase DPE2
• Gene Name: DPE2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 955
• Subcellular Localization: Cytoplasm, cytosol .
• Protein Description: Cytosolic alpha-glucanotransferase essential for the cytosolic metabolism of maltose, an intermediate on the pathway by which starch is converted to sucrose in leaves at night. Metabolizes maltose exported from the chloroplast and is specific for beta-maltose. May play a role in freezing tolerance. Temperature drop induces inactivation of DPE2 that leads to rapid accumulation of maltose, a solute that protects cells from freezing damage..
• Protein Sequence: MMNLGSLSLSTSKSSKPMVSISFWIPYFTHWGESLLVCGSAPGLGSGNVKKGLLLKPSQQDDQLIWSGSVSVPPGFSSDYCYYVVDDSKSVLRSEFGMKRKLVVPETLTGGESVHLRDLWQSGDQALPFRSAFKDVIFHHSFDVKVEKPLGVFMNKSDQDDSVVVQFKICCPDIGEGTSVYVLGTPEKLGNWKVENGLRLNYVDDSIWEADCLIPKADFPIKYRYCKVQKEDSIGFESGGNRELSLHSIGSKQEYIVMSDGLFRAMPWRGAGVAVPMFSVRSEDDVGVGEFLDLKLLVDWAVDSGLHLVQLLPVNDTSVHKMWWDSYPYSSLSVFALHPLYLRVQALSERLPEDIKEEIQKAKNQLDKNDVDYEATMETKLSIAKKIFDIEKDQTLNSSTFQKFFSENEGWLKPYAAFCFLRDFFETSDHSQWGTFSDYTDDKLEKLISKDNLHYNTICFHYYIQYHLHVQLSAAAEYARKKGVVLKGDLPIGVDRNSVDTWVYRNLFRMNTSTGAPPDYFDKNGQNWGFPTYNWEEMSKDNYAWWRARLTQMGKYFTAYRIDHILGFFRIWELPAHAMTGLVGKFRPSIPLSQEELEKEGIWDFDRLSKPYIQKKFLEEKFGDFWPFIASNFLNETQKDMYEFKEDCNTEKKIVAKLKSLAEKSLLLENEDKVRRDVFDILRNVVLIKDPEDARKFYPRFNIEDTSSFQDLDDHSKNVLKRLYYDYYFQRQEDLWRKNALKTLPALLNSSNMLACGEDLGLIPSCVHPVMQELGLVGLRIQRMPSESDVKFGIPSNYDYMTVCAPSCHDCSTLRAWWEEDEERRQQYFKEVIGVDGIPPSQCIPEITHFILRQHVEAPSMWAIFPLQDMMALKEEYTTRPATEETINDPTNPKHYWRYRVHVTLDSLLKDTDLKSTIKNLVSSSGRSVPANVSGEDINKSRGEVIANGSTKPNP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MMNLGSLS -------CCCCCCEE	3.47	22223895
69	Phosphorylation	DQLIWSGSVSVPPGF CCEEEECEEECCCCC	13.00	28011693
71	Phosphorylation	LIWSGSVSVPPGFSS EEEECEEECCCCCCC	30.51	28011693
245	Phosphorylation	SGGNRELSLHSIGSK CCCCCEEEEEECCCC	21.20	19880383
248	Phosphorylation	NRELSLHSIGSKQEY CCEEEEEECCCCCEE	33.66	19880383
251	Phosphorylation	LSLHSIGSKQEYIVM EEEEECCCCCEEEEE	29.51	19880383
706	Phosphorylation	PRFNIEDTSSFQDLD CCCCCCCCCCCCCCC	17.30	19880383
707	Phosphorylation	RFNIEDTSSFQDLDD CCCCCCCCCCCCCCH	41.29	19880383
708	Phosphorylation	FNIEDTSSFQDLDDH CCCCCCCCCCCCCHH	29.08	19880383
716	Phosphorylation	FQDLDDHSKNVLKRL CCCCCHHHHHHHHHH	32.68	19880383
786	Phosphorylation	LRIQRMPSESDVKFG EEEEECCCHHCCCCC	40.15	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DPE2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DPE2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DPE2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUMO3_ARATH	SUMO3	physical	20855607

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.