DMRTA_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DMRTA_HUMAN
• UniProt AC: Q5VZB9
• Protein Name: Doublesex- and mab-3-related transcription factor A1
• Gene Name: DMRTA1
• Organism: Homo sapiens (Human).
• Sequence Length: 504
• Subcellular Localization: Nucleus .
• Protein Sequence: MERSQCGSRDRGVSGRPHLAPGLVVAAPPPPSPALPVPSGMQVPPAFLRPPSLFLRAAAAAAAAAAATSGSGGCPPAPGLESGVGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLQRLLCSGLSWPPGGRASGGGGRAENPQSTGGPAAGAALGLGALRQASGSATPAFEVFQQDYPEEKQEQKESKCESCQNGQEELISKSHQLYLGSSSRSNGVIGKQSIGSSISEYSNKPDSILSPHPGEQSGGEESPRSLSSSDLESGNESEWVKDLTATKASLPTVSSRPRDPLDILTKIFPNYRRSRLEGILRFCKGDVVQAIEQVLNGKEHKPDNRNLANSEELENTAFQRASSFSLAGIGFGTLGNKSAFSPLQTTSASYGGDSSLYGVNPRVGISPLRLAYSSAGRGLSGFMSPYLTPGLVPTLPFRPALDYAFSGMIRDSSYLSSKDSITCGRLYFRPNQDNP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
68	Phosphorylation	AAAAAAATSGSGGCP HHHHHHHHCCCCCCC	28.97	26074081
69	Phosphorylation	AAAAAATSGSGGCPP HHHHHHHCCCCCCCC	26.66	26074081
71	Phosphorylation	AAAATSGSGGCPPAP HHHHHCCCCCCCCCC	31.60	26074081
82	Phosphorylation	PPAPGLESGVGAVGC CCCCCCCCCCCCCCC	43.77	26074081
91	Phosphorylation	VGAVGCGYPRTPKCA CCCCCCCCCCCCCCH	8.13	26074081
225	Methylation	PEEKQEQKESKCESC HHHHHHHHHHHCHHC	64.30	-
228	Methylation	KQEQKESKCESCQNG HHHHHHHHCHHCCCH	43.01	-
276	Phosphorylation	EYSNKPDSILSPHPG HHCCCCCCCCCCCCC	33.68	22468782
286	Phosphorylation	SPHPGEQSGGEESPR CCCCCCCCCCCCCCC	44.45	22468782
294	Phosphorylation	GGEESPRSLSSSDLE CCCCCCCCCCHHHCC	35.67	22468782
321	Phosphorylation	ATKASLPTVSSRPRD HCCCCCCCCCCCCCC	38.01	22210691
323	Phosphorylation	KASLPTVSSRPRDPL CCCCCCCCCCCCCHH	24.09	22210691
324	Phosphorylation	ASLPTVSSRPRDPLD CCCCCCCCCCCCHHH	41.80	-
340	Phosphorylation	LTKIFPNYRRSRLEG HHHHCCCHHHHHHHH	13.98	24043423
391	Phosphorylation	NTAFQRASSFSLAGI HHHHHHHHHHCCCCE	33.82	28348404
392	Phosphorylation	TAFQRASSFSLAGIG HHHHHHHHHCCCCEE	20.19	28348404
394	Phosphorylation	FQRASSFSLAGIGFG HHHHHHHCCCCEEEC	21.18	28348404
435	Phosphorylation	VNPRVGISPLRLAYS CCCCCCCCHHHHHHC	16.38	19664994
441	Phosphorylation	ISPLRLAYSSAGRGL CCHHHHHHCCCCCCC	14.03	22817900
443	Phosphorylation	PLRLAYSSAGRGLSG HHHHHHCCCCCCCCC	23.28	22817900
455	Phosphorylation	LSGFMSPYLTPGLVP CCCCCCCCCCCCCCC	18.85	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DMRTA_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DMRTA_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DMRTA_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ORC5_HUMAN	ORC5	physical	21988832
STA5B_HUMAN	STAT5B	physical	21988832

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.