dbPTM

DLP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DLP1_HUMAN
UniProt AC	Q86YH6
Protein Name	Decaprenyl-diphosphate synthase subunit 2
Gene Name	PDSS2
Organism	Homo sapiens (Human).
Sequence Length	399
Subcellular Localization	Mitochondrion .
Protein Description	Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10..
Protein Sequence	MNFRQLLLHLPRYLGASGSPRRLWWSPSLDTISSVGSWRGRSSKSPAHWNQVVSEAEKIVGYPTSFMSLRCLLSDELSNIAMQVRKLVGTQHPLLTTARGLVHDSWNSLQLRGLVVLLISKAAGPSSVNTSCQNYDMVSGIYSCQRSLAEITELIHIALLVHRGIVNLNELQSSDGPLKDMQFGNKIAILSGDFLLANACNGLALLQNTKVVELLASALMDLVQGVYHENSTSKESYITDDIGISTWKEQTFLSHGALLAKSCQAAMELAKHDAEVQNMAFQYGKHMAMSHKINSDVQPFIKEKTSDSMTFNLNSAPVVLHQEFLGRDLWIKQIGEAQEKGRLDYAKLRERIKAGKGVTSAIDLCRYHGNKALEALESFPPSEARSALENIVFAVTRFS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	Phosphorylation	SPRRLWWSPSLDTIS CCCCCEECCCCCCCC	7.95	24667141
28	Phosphorylation	RRLWWSPSLDTISSV CCCEECCCCCCCCCC	33.10	24667141
54	Phosphorylation	AHWNQVVSEAEKIVG HHHHHHHHHHHHHHC	32.03	-
86	Acetylation	NIAMQVRKLVGTQHP HHHHHHHHHHCCCCC	48.98	7851879
97	Phosphorylation	TQHPLLTTARGLVHD CCCCHHHCCHHHHCC	17.83	24719451
306	Phosphorylation	PFIKEKTSDSMTFNL HHHCCCCCCCCEEEC	38.46	21601212
332	Ubiquitination	LGRDLWIKQIGEAQE HCCCCHHHHHHHHHH	25.04	-
356	Malonylation	RERIKAGKGVTSAID HHHHHCCCCCCHHHH	55.88	26320211

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DLP1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DLP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DLP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DLP1_HUMAN

Related Literatures of Post-Translational Modification