dbPTM

DJ1A_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DJ1A_ARATH
UniProt AC	Q9FPF0
Protein Name	Protein DJ-1 homolog A
Gene Name	DJ1A
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	392
Subcellular Localization	Cytoplasm, cytosol . Nucleus .
Protein Description	Involved in oxidative stress response. Confers protection against diverse stresses by binding both CSD1 and GPX2 and mediating the cytosolic activation of the Cu-Zn-dependent superoxide dismutase activity of CSD1..
Protein Sequence	MASFTKTVLIPIAHGTEPLEAVAMITVLRRGGADVTVASVETQVGVDACHGIKMVADTLLSDITDSVFDLIVLPGGLPGGETLKNCKSLENMVKKQDSDGRLNAAICCAPALALGTWGLLEGKKATGYPVFMEKLAATCATAVESRVQIDGRIVTSRGPGTTIEFSITLIEQLFGKEKADEVSSILLLRPNPGEEFTFTELNQTNWSFEDTPQILVPIAEESEEIEAIALVDILRRAKANVVIAAVGNSLEVEGSRKAKLVAEVLLDEVAEKSFDLIVLPGGLNGAQRFASCEKLVNMLRKQAEANKPYGGICASPAYVFEPNGLLKGKKATTHPVVSDKLSDKSHIEHRVVVDGNVITSRAPGTAMEFSLAIVEKFYGREKALQLGKATLV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
88	Phosphorylation	ETLKNCKSLENMVKK HHHHCHHHHHHHHHH	23776212
298	Sulfoxidation	SCEKLVNMLRKQAEA HHHHHHHHHHHHHHH	25693801
378	Phosphorylation	LAIVEKFYGREKALQ HHHHHHHHCHHHHHH	25368622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DJ1A_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DJ1A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DJ1A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
SODC1_ARATH	CSD1	physical	20406884
GPX2_ARATH	GPX2	physical	20406884

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DJ1A_ARATH

Related Literatures of Post-Translational Modification