DFFB_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DFFB_MOUSE
• UniProt AC: O54788
• Protein Name: DNA fragmentation factor subunit beta
• Gene Name: Dffb
• Organism: Mus musculus (Mouse).
• Sequence Length: 344
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology..
• Protein Sequence: MCAVLRQPKCVKLRALHSACKFGVAARSCQELLRKGCVRFQLPMPGSRLCLYEDGTEVTDDCFPGLPNDAELLLLTAGETWHGYVSDITRFLSVFNEPHAGVIQAARQLLSDEQAPLRQKLLADLLHHVSQNITAETREQDPSWFEGLESRFRNKSGYLRYSCESRIRGYLREVSAYTSMVDEAAQEEYLRVLGSMCQKLKSVQYNGSYFDRGAEASSRLCTPEGWFSCQGPFDLESCLSKHSINPYGNRESRILFSTWNLDHIIEKKRTVVPTLAEAIQDGREVNWEYFYSLLFTAENLKLVHIACHKKTTHKLECDRSRIYRPQTGSRRKQPARKKRPARKR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
311	Phosphorylation	HIACHKKTTHKLECD EEECCCCCCCCCCCC	38.65	28576409
312	Phosphorylation	IACHKKTTHKLECDR EECCCCCCCCCCCCH	26.37	28576409

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DFFB_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DFFB_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DFFB_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DFFA_MOUSE	Dffa	physical	15572351

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.