DBP5_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DBP5_SCHPO
• UniProt AC: Q09747
• Protein Name: ATP-dependent RNA helicase dbp5
• Gene Name: dbp5
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 503
• Subcellular Localization: Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nuclear pore complex cytoplasmic fibrils..
• Protein Description: ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity)..
• Protein Sequence: MSTTLGQESKTDWASLDSDEEVQRISDKVNQLNTSENKNEDQKATNLSDRLGPKITENVDAKSEQDKATNTIAEDANTKQSENDESNLIPNKNEVRVKLADLQADPNSPLFSVKSFEELELKPELLKGIYSMKFQKPSKIQEKALPLLLSNPPRNMIGQSQSGTGKTAAFALTMLSRVDASVPKPQAICLAPSRELARQIMDVVTEMGKYTEVKTAFGIKDSVPKGAKIDAQIVIGTPGTVMDLMKRRQLDARDIKVFVLDEADNMLDQQGLGDQSMRIKHLLPRNTQIVLFSATFSERVEKYAERFAPNANEIRLKTEELSVEGIKQLYMDCQSEEHKYNVLVELYGLLTIGQSIIFCKKKDTAEEIARRMTADGHTVACLTGNLEGAQRDAIMDSFRVGTSKVLVTTNVIARGIDVSQVNLVVNYDMPLDQAGRPDPQTYLHRIGRTGRFGRVGVSINFVHDKKSWEEMNAIQEYFQRPITRVPTDDYEELEKVVKNALKM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	TLGQESKTDWASLDS CCCCCCCCCHHHCCC	46.16	25720772
15	Phosphorylation	ESKTDWASLDSDEEV CCCCCHHHCCCHHHH	28.58	28889911
18	Phosphorylation	TDWASLDSDEEVQRI CCHHHCCCHHHHHHH	52.82	28889911
26	Phosphorylation	DEEVQRISDKVNQLN HHHHHHHHHHHHHHC	33.30	21712547
34	Phosphorylation	DKVNQLNTSENKNED HHHHHHCCCCCCCHH	46.11	25720772
35	Phosphorylation	KVNQLNTSENKNEDQ HHHHHCCCCCCCHHH	37.79	29996109
48	Phosphorylation	DQKATNLSDRLGPKI HHHHCCHHHHHCHHH	23.82	24763107
56	Phosphorylation	DRLGPKITENVDAKS HHHCHHHHCCCCCCC	27.86	24763107
63	Phosphorylation	TENVDAKSEQDKATN HCCCCCCCHHHHHHH	42.06	24763107
81	Phosphorylation	EDANTKQSENDESNL HHHCCCCCCCCCCCC	39.67	21712547
86	Phosphorylation	KQSENDESNLIPNKN CCCCCCCCCCCCCCC	39.54	24763107
115	Phosphorylation	SPLFSVKSFEELELK CCCCCCCCHHHHCCC	35.42	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DBP5_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DBP5_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DBP5_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DBP5_SCHPO	dbp5	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.