CY561_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CY561_HUMAN
• UniProt AC: P49447
• Protein Name: Cytochrome b561
• Gene Name: CYB561
• Organism: Homo sapiens (Human).
• Sequence Length: 251
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: Secretory vesicle-specific electron transport protein..
• Protein Sequence: MEGGAAAATPTALPYYVAFSQLLGLTLVAMTGAWLGLYRGGIAWESDLQFNAHPLCMVIGLIFLQGNALLVYRVFRNEAKRTTKVLHGLLHIFALVIALVGLVAVFDYHRKKGYADLYSLHSWCGILVFVLYFVQWLVGFSFFLFPGASFSLRSRYRPQHIFFGATIFLLSVGTALLGLKEALLFNLGGKYSAFEPEGVLANVLGLLLACFGGAVLYILTRADWKRPSQAEEQALSMDFKTLTEGDSPGSQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MEGGAAAA -------CCCCCCCC	11.02	-
132	Phosphorylation	GILVFVLYFVQWLVG HHHHHHHHHHHHHHH	9.08	28985074
141	Phosphorylation	VQWLVGFSFFLFPGA HHHHHHHHHHHCCCC	14.79	28985074
149	Phosphorylation	FFLFPGASFSLRSRY HHHCCCCCCCCCCCC	22.68	24719451
151	Phosphorylation	LFPGASFSLRSRYRP HCCCCCCCCCCCCCC	22.00	24719451
154	Phosphorylation	GASFSLRSRYRPQHI CCCCCCCCCCCCHHH	38.67	28985074
225	Ubiquitination	ILTRADWKRPSQAEE HHHHCCCCCCCHHHH	55.78	-
236	Phosphorylation	QAEEQALSMDFKTLT HHHHHHHCCCHHHCC	21.22	25849741
240	Ubiquitination	QALSMDFKTLTEGDS HHHCCCHHHCCCCCC	38.06	2190698
243	Phosphorylation	SMDFKTLTEGDSPGS CCCHHHCCCCCCCCC	43.06	25627689
247	Phosphorylation	KTLTEGDSPGSQ--- HHCCCCCCCCCC---	41.85	25159151
250	Phosphorylation	TEGDSPGSQ------ CCCCCCCCC------	35.78	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CY561_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CY561_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CY561_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EDA_HUMAN	EDA	physical	25416956
RNF5_HUMAN	RNF5	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.