CXL13_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CXL13_HUMAN
• UniProt AC: O43927
• Protein Name: C-X-C motif chemokine 13
• Gene Name: CXCL13
• Organism: Homo sapiens (Human).
• Sequence Length: 109
• Subcellular Localization: Secreted.
• Protein Description: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5..
• Protein Sequence: MKFISTSLLLMLLVSSLSPVQGVLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGCPRKEIIVWKKNKSIVCVDPQAEWIQRMMEVLRKRSSSTLPVPVFKRKIP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	LLLMLLVSSLSPVQG HHHHHHHHCCCCCCC	26.07	25954137
28	Phosphorylation	QGVLEVYYTSLRCRC CCHHHHHHEEEEEEE	8.60	25954137
39	Phosphorylation	RCRCVQESSVFIPRR EEEEEECCCEEEEHH	18.08	-
40	Phosphorylation	CRCVQESSVFIPRRF EEEEECCCEEEEHHH	21.94	-
63	Sumoylation	RGNGCPRKEIIVWKK CCCCCCCCEEEEEEC	38.11	-
63	Sumoylation	RGNGCPRKEIIVWKK CCCCCCCCEEEEEEC	38.11	-
69	Ubiquitination	RKEIIVWKKNKSIVC CCEEEEEECCCEEEE	35.26	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CXL13_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CXL13_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CXL13_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EF1G_HUMAN	EEF1G	physical	16169070
CDN1A_HUMAN	CDKN1A	physical	24027428

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.