dbPTM

CWC24_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CWC24_SCHPO
UniProt AC	Q9P6R8
Protein Name	Pre-mRNA-splicing factor cwf24
Gene Name	cwf24
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	533
Subcellular Localization	Nucleus.
Protein Description	Involved in mRNA splicing..
Protein Sequence	MEQKNLNINQASGSKINTELAVPIFQSRRRHRPRQGLKRKKGFKRDDDSGGSSESSNEDMRDNIPIVSGRKKTVRLNRLQRESEQFENSALKDINVEYQSNLSATGESVNTTTVSAINEDTREVILGRPSPKLANQSTLPTELFQSQNDYSRFLPKRKDFEKKSQVGPVLSSNASTVRMNTIIDYQPDVCKDYKLTGYCGYGDTCKFLHMREDYKAGWQLDREWDSVQEKYKKGAKLEEGMVKNEKKEDIPFVCLICKKDYRSPIATTCGHHFCEQCAITRYRKTPTCIQCGADTKGLFSVDKNFDRLLKNRKSKNDEAVKQKVGGFESNNSATTEVSERKDREASFQGFADTLAKPNTSAQQKMPSLGDNSNTIISKYFIREITESNIVHFKRLVRVVLEASYSDKFYRLVLKNPDYARIATFEDKFVGAISSLVAEDNSLYVTVLCVLAPYRCLGIGSLLIDHVKKTAINNNIDRISLHVQTTNESVIKWYTAHGFKIVKQINDFYRRLENKSAFYMVCPLSAHNNIISNH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
130	Phosphorylation	EVILGRPSPKLANQS HHHCCCCCHHHCCCC	33.05	28889911
346	Phosphorylation	ERKDREASFQGFADT HHHHHHHHHHHHHHH	17.22	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CWC24_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CWC24_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CWC24_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MTO1_SCHPO	SPBC30B4.06c	genetic	22681890
H31_SCHPO	hht3	genetic	22681890
YOM1_SCHPO	SPBPB7E8.01	genetic	22681890
YH7G_SCHPO	SPBC16G5.16	physical	26771498
TAS3_SCHPO	tas3	physical	26771498
SEC6_SCHPO	sec6	physical	26771498
MTC1_SCHPO	SPCC1322.09	physical	26771498
IPK1_SCHPO	ipk1	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CWC24_SCHPO

Related Literatures of Post-Translational Modification