CWC15_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CWC15_DROME
• UniProt AC: Q9V3B6
• Protein Name: Protein CWC15 homolog
• Gene Name: c12.1
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 259
• Protein Description: Involved in pre-mRNA splicing..
• Protein Sequence: MTTAARPTFDPARGGSGRGEKDLSALSKQYSSRDLPGHTKLKYRETGQGTSDENRNRDFRKELEEREREARSGTGATSSSSGKALPSIVRKAIEANNAGGGSSAAKRSKPDAGQQQAQQAAQQQAANMDADEPLDNDSSDSDSDSDDDDAALLAELQKIKQERLQETARRESEKKQEDERIRMENILSGNPLMNYEPGTAASAAGRASGLGGDLKIKRRWDDDVVFKNCARSAPDKKTHFVNDALRSDFHKKFMDKYIK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Acetylation	GGSGRGEKDLSALSK CCCCCCHHHHHHHHH	67.79	21791702
103	Phosphorylation	NNAGGGSSAAKRSKP CCCCCCCCCHHHCCC	35.20	22668510
208	Phosphorylation	ASAAGRASGLGGDLK HHHHHHHCCCCCCCE	32.94	21082442
256	Acetylation	FHKKFMDKYIK---- HHHHHHHHHCC----	36.77	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CWC15_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CWC15_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CWC15_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RG92B_DROME	RhoGAP92B	physical	14605208

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.