CUE5_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CUE5_SCHPO
• UniProt AC: O14319
• Protein Name: CUE domain-containing protein 5
• Gene Name: SPBC16E9.02c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 569
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MASEQSNPRLPRRPPYMAEKARATLKEAFPNTDDAIIRAVLAASGYKLEPAFNALLGLSDPQVAEEMEQAETSYAYDTAAHDDPVQRQLEEDERCARELANRYNSHRPERRRKTNNDRRNYPPQNRTAKPNDNDGDDYSFFEDDLPVIKDTFMRGFQSFKQRSMEWVENIASKFDGEEEDDDDEKYSAPSKIYPSPRRSTAATLESAYEERPPSLPRRKPSRPGTAITLPPYESDPHMLNEKDFERLRLESSSSPMMRRSSLNSNRRSVESSSSAAFVEGQSFILDSNGAIEVANSAFALDDSDLESAYNEELEMKKDTSKPTASTKEVVVEKKPDESRKQAARTLETVSEEQMGSSNAKSKVLTSEPKDSTSVEAEKTETDEPAVGKGASDVSDTAEISEKTEAKNADSEANLEEKSDVGEEKESKDENNKASLHKDVEEKDTKITNEDTGKTETDVKAKETDSIEANDKDEKTDSKETEDKVEETESKEADVKAKETDSIEVDDKEEKTDSKETADKVEQTDSKDTNEKPAKDDNKEANEKAEKVDSKDVKEKIEEAADLQNSGKET

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
72	Phosphorylation	EEMEQAETSYAYDTA HHHHHHHHHHHHHHH	30.01	29996109
73	Phosphorylation	EMEQAETSYAYDTAA HHHHHHHHHHHHHHC	10.16	29996109
74	Phosphorylation	MEQAETSYAYDTAAH HHHHHHHHHHHHHCC	19.32	29996109
76	Phosphorylation	QAETSYAYDTAAHDD HHHHHHHHHHHCCCC	12.95	29996109
139	Phosphorylation	DNDGDDYSFFEDDLP CCCCCCCCHHCCCCH	30.38	24763107
195	Phosphorylation	APSKIYPSPRRSTAA CCCCCCCCCCCCHHH	17.67	28889911
199	Phosphorylation	IYPSPRRSTAATLES CCCCCCCCHHHHHHH	24.55	29996109
200	Phosphorylation	YPSPRRSTAATLESA CCCCCCCHHHHHHHH	20.64	28889911
203	Phosphorylation	PRRSTAATLESAYEE CCCCHHHHHHHHHHH	28.70	25720772
206	Phosphorylation	STAATLESAYEERPP CHHHHHHHHHHHCCC	38.98	25720772
208	Phosphorylation	AATLESAYEERPPSL HHHHHHHHHHCCCCC	27.83	29996109
214	Phosphorylation	AYEERPPSLPRRKPS HHHHCCCCCCCCCCC	54.40	28889911
251	Phosphorylation	FERLRLESSSSPMMR HHHHHCCCCCCCCHH	39.86	28889911
252	Phosphorylation	ERLRLESSSSPMMRR HHHHCCCCCCCCHHH	26.01	25720772
253	Phosphorylation	RLRLESSSSPMMRRS HHHCCCCCCCCHHHH	47.98	25720772
254	Phosphorylation	LRLESSSSPMMRRSS HHCCCCCCCCHHHHH	20.82	28889911
345	Phosphorylation	SRKQAARTLETVSEE HHHHHHHHHHHHCHH	24.99	21712547
350	Phosphorylation	ARTLETVSEEQMGSS HHHHHHHCHHHHCCC	42.72	27738172
371	Phosphorylation	LTSEPKDSTSVEAEK CCCCCCCCCCEEEEE	28.80	29996109
372	Phosphorylation	TSEPKDSTSVEAEKT CCCCCCCCCEEEEEC	47.10	24763107
373	Phosphorylation	SEPKDSTSVEAEKTE CCCCCCCCEEEEECC	23.16	28889911
379	Phosphorylation	TSVEAEKTETDEPAV CCEEEEECCCCCCCC	35.31	24763107
381	Phosphorylation	VEAEKTETDEPAVGK EEEEECCCCCCCCCC	51.39	29996109
391	Phosphorylation	PAVGKGASDVSDTAE CCCCCCCCCCHHHHH	47.41	24763107
394	Phosphorylation	GKGASDVSDTAEISE CCCCCCCHHHHHHHH	33.95	24763107
396	Phosphorylation	GASDVSDTAEISEKT CCCCCHHHHHHHHHH	20.77	21712547
410	Phosphorylation	TEAKNADSEANLEEK HHHHCCCCCCCHHHC	35.88	29996109
418	Phosphorylation	EANLEEKSDVGEEKE CCCHHHCCCCCCHHH	40.59	24763107
451	Phosphorylation	TKITNEDTGKTETDV CCCCCCCCCCCHHCC	34.11	25720772
454	Phosphorylation	TNEDTGKTETDVKAK CCCCCCCCHHCCCHH	45.52	25720772
456	Phosphorylation	EDTGKTETDVKAKET CCCCCCHHCCCHHHC	51.85	25720772
463	Phosphorylation	TDVKAKETDSIEAND HCCCHHHCCCCCCCC	34.05	24763107
465	Phosphorylation	VKAKETDSIEANDKD CCHHHCCCCCCCCCC	29.73	25720772
487	Phosphorylation	TEDKVEETESKEADV HHHHHHHHHHHHHHH	31.86	21712547
489	Phosphorylation	DKVEETESKEADVKA HHHHHHHHHHHHHCC	43.12	21712547
499	Phosphorylation	ADVKAKETDSIEVDD HHHCCCCCCCEECCC	34.05	24763107
501	Phosphorylation	VKAKETDSIEVDDKE HCCCCCCCEECCCCH	28.24	21712547
565	Phosphorylation	EAADLQNSGKET--- HHHHHHHCCCCC---	37.98	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CUE5_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CUE5_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CUE5_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PST2_SCHPO	pst2	genetic	19547744

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.