CNTP3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CNTP3_HUMAN
• UniProt AC: Q9BZ76
• Protein Name: Contactin-associated protein-like 3
• Gene Name: CNTNAP3
• Organism: Homo sapiens (Human).
• Sequence Length: 1288
• Subcellular Localization: Isoform 1: Cell membrane ; Single-pass type I membrane protein .; Isoform 2: Secreted .
• Protein Sequence: MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYRLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSYLDLNFEISFGGIPTPGRSRAFRRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELRRGSGSFVLFLKDGKLKLSLFQPGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAVLIDSGDTYYFGGCLDNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTADAAWTVVQHGGPDAVTLRGAPSGHPRSAVSFAYAAGAGQLRSAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLSQKEHLPVTQIVMTDAGRPHSEAAYTLGPLLCRGDQSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSTKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPADEGEPLVNADRRDSAVIGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	DCDAPLASALPRSSF CCCCCHHHCCCCCCC	37.71	24719451
77 (in isoform 2)	Ubiquitination	-	31.17	21906983
77 (in isoform 1)	Ubiquitination	-	31.17	21906983
77	Ubiquitination	WTPLVSNKYQWLQID CCCCCCCEEEEEEEE	31.17	22817900
209	Phosphorylation	KPIRDVISLKFKAMQ CCHHHHHHHHHEEHH	25.92	24719451
285	N-linked_Glycosylation	ELLDTQVNFTVDKHT HHHHCEECEEEECCC	19.63	UniProtKB CARBOHYD
359	N-linked_Glycosylation	PQILMMGNVSFSCPQ CCEEEEECEEEECCC	14.36	UniProtKB CARBOHYD
361	Phosphorylation	ILMMGNVSFSCPQPQ EEEEECEEEECCCCC	18.55	-
369	Phosphorylation	FSCPQPQTVPVTFLS EECCCCCCEEEEEEC	33.20	25954137
376	Phosphorylation	TVPVTFLSSRSYLAL CEEEEEECCCCEEEC	21.36	25954137
379	Phosphorylation	VTFLSSRSYLALPGN EEEECCCCEEECCCC	26.84	25954137
380	Phosphorylation	TFLSSRSYLALPGNS EEECCCCEEECCCCC	8.55	22817900
416	Phosphorylation	FGELRRGSGSFVLFL EEEEECCCCEEEEEE	29.47	22210691
418	Phosphorylation	ELRRGSGSFVLFLKD EEECCCCEEEEEEEC	17.55	22210691
424	Ubiquitination	GSFVLFLKDGKLKLS CEEEEEEECCEEEEE	58.04	33845483
429	Acetylation	FLKDGKLKLSLFQPG EEECCEEEEEEECCC	39.24	24848137
441	N-linked_Glycosylation	QPGQSPRNVTAGAGL CCCCCCCCEECCCCC	38.58	UniProtKB CARBOHYD
497	N-linked_Glycosylation	YFGGCLDNSSGSGCK EECCCCCCCCCCCCC	25.73	UniProtKB CARBOHYD
536	Phosphorylation	VQQGALGSFRDLQID EECCCCCCCCCCCCC	20.26	24719451
623	N-linked_Glycosylation	GPFLVYCNMTADAAW CCEEEEECCCHHHEE	17.10	UniProtKB CARBOHYD
653	Phosphorylation	APSGHPRSAVSFAYA CCCCCCCHHHHHHHH	37.16	-
706	N-linked_Glycosylation	SWWVGRTNETHTSWG EEEECCCCCCCCCCC	51.30	UniProtKB CARBOHYD
823	Phosphorylation	DVCFFFKTTVSSGVF EEEEEEEEEECCCCE	27.55	28787133
824	Phosphorylation	VCFFFKTTVSSGVFM EEEEEEEEECCCCEE	20.98	28787133
827	Phosphorylation	FFKTTVSSGVFMENL EEEEEECCCCEEHHC	34.34	28787133
1023	N-linked_Glycosylation	EHYTLSENSSSLVSS EEEECCCCHHHHHHH	43.76	UniProtKB CARBOHYD
1045	Phosphorylation	TREMITLSFRTTRTP CCEEEEEEECCCCCH	12.20	24719451
1073	N-linked_Glycosylation	LSVILANNGSLQIRY HHHHCCCCCEEEEEE	35.50	UniProtKB CARBOHYD
1120	N-linked_Glycosylation	AVVMVEVNQSTKKQV EEEEEEECCCCCCEE	19.31	UniProtKB CARBOHYD
1131	Phosphorylation	KKQVILSSGTEFNAV CCEEEECCCCCHHHH	46.41	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CNTP3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CNTP3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CNTP3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
APBA1_HUMAN	APBA1	physical	12093160

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.