CMTA2_HUMAN - dbPTM
CMTA2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CMTA2_HUMAN
UniProt AC O94983
Protein Name Calmodulin-binding transcription activator 2
Gene Name CAMTA2
Organism Homo sapiens (Human).
Sequence Length 1202
Subcellular Localization Nucleus .
Protein Description Transcription activator. May act as tumor suppressor..
Protein Sequence MNTKDTTEVAENSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMECLYGCYVHSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHGIKWSCGNGTEEFSVEHLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPEWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDNQFRMSILERLEQMEKRMAEIAAAGQVPCQGPDAPPVQDEGQGPGFEARVVVLVESMIPRSTWKGPERLAHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFRWNRQALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFVGLPEAGASMRERTGAVGLSETMSWLASYLENVDHFPSSTPPSELPFERGRLAVPSAPSWAEFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGLAT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7 (in isoform 3)Phosphorylation-38.3024719451
15 (in isoform 3)Phosphorylation-28.74-
237PhosphorylationSGGLGSGSLTHKCSS
CCCCCCCCCCCCCCC		31.6224667141
251PhosphorylationSTKHRIISPKVEPRA
CCCCEECCCCCCCCE		19.1224719451
293PhosphorylationAHTSPSSSSSSSSSG
CCCCCCCCCCCCCCC		38.28-
294PhosphorylationHTSPSSSSSSSSSGF
CCCCCCCCCCCCCCC		35.8723663014
295PhosphorylationTSPSSSSSSSSSGFA
CCCCCCCCCCCCCCC		35.87-
296PhosphorylationSPSSSSSSSSSGFAE
CCCCCCCCCCCCCCC		35.87-
318PhosphorylationPPTSRGGSSRGGTAI
CCCCCCCCCCCCEEE		21.49-
319PhosphorylationPTSRGGSSRGGTAIL
CCCCCCCCCCCEEEE		37.91-
323PhosphorylationGGSSRGGTAILLLTG
CCCCCCCEEEEEECC		17.22-
339PhosphorylationEQRAGGLTPTRHLAP
HHHCCCCCCCCCCCC		26.3724719451
383PhosphorylationDPDRFLNSPQRGQTY
CHHHCCCCCCCCCCC		25.2623312004
449PhosphorylationFFIQDDDSGEELKGH
EEEECCCCCCCCCCC		55.9128348404
464PhosphorylationGAAPPIPSPPPSPPP
CCCCCCCCCCCCCCC		51.2422777824
468PhosphorylationPIPSPPPSPPPSPAP
CCCCCCCCCCCCCCC		56.6722777824
472PhosphorylationPPPSPPPSPAPLEPS
CCCCCCCCCCCCCCC		39.1922777824
472 (in isoform 6)Phosphorylation-39.1927251275
479PhosphorylationSPAPLEPSSRVGRGE
CCCCCCCCCCCCCCC		22.7723090842
480PhosphorylationPAPLEPSSRVGRGEA
CCCCCCCCCCCCCCC		41.5223090842
487 (in isoform 6)Phosphorylation-15.8327251275
491 (in isoform 6)Phosphorylation-13.3427251275
495 (in isoform 6)Phosphorylation-10.4827251275
596PhosphorylationAHEVGLVSLQVAGRE
HHHCEEEEEEECCCC		20.37-
788PhosphorylationQALSIPDSLGRLPLS
HHHCCCCCCCCCCCC		27.63-
875PhosphorylationPLPASEMTMEDMAPG
CCCHHHCCHHHCCCC		17.2325278378
885PhosphorylationDMAPGQLSSGVPEAP
HCCCCCCCCCCCCCC		19.7025278378
886PhosphorylationMAPGQLSSGVPEAPL
CCCCCCCCCCCCCCE		53.0225278378
898PhosphorylationAPLLLMDYEATNSKG
CCEEEEEEECCCCCC		8.1025278378
901PhosphorylationLLMDYEATNSKGPLS
EEEEEECCCCCCCHH		28.2525278378
903PhosphorylationMDYEATNSKGPLSSL
EEEECCCCCCCHHHC		34.3425278378
1057PhosphorylationEAARVIQTAFRKYKG
HHHHHHHHHHHHHCC		19.35-
1084AcetylationVIQRCYRKYKQLTWI
HHHHHHHHHHHHHHH		30.2661111
1086AcetylationQRCYRKYKQLTWIAL
HHHHHHHHHHHHHHH		41.7090203
1094AcetylationQLTWIALKFALYKKM
HHHHHHHHHHHHHHH		21.4090207
1099AcetylationALKFALYKKMTQAAI
HHHHHHHHHHHHHHH		36.6090211
1158 (in isoform 6)Phosphorylation-27.4627642862
1159PhosphorylationLPARNKGSFLTKKQD
CCCCCCCCCCCHHHH		20.77-
1164UbiquitinationKGSFLTKKQDQAARK
CCCCCCHHHHHHHHH		54.60-
1218 (in isoform 6)Phosphorylation--
1222 (in isoform 6)Phosphorylation--
1226 (in isoform 6)Phosphorylation--
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CMTA2_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CMTA2_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CMTA2_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HDAC5_HUMANHDAC5physical
16678093
F192A_HUMANFAM192Aphysical
26186194
PSME3_HUMANPSME3physical
26186194
F192A_HUMANFAM192Aphysical
28514442
PSME3_HUMANPSME3physical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CMTA2_HUMAN

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Related Literatures of Post-Translational Modification

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