CL050_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CL050_HUMAN
• UniProt AC: Q8NA57
• Protein Name: Uncharacterized protein C12orf50
• Gene Name: C12orf50
• Organism: Homo sapiens (Human).
• Sequence Length: 414
• Protein Sequence: MEMQQNCSISCFWETQPLGCVKISCIFYHSKPRNINGLFLPPSSNITLQKEIQEGIPLQSQSQEPLKPQENISRPIHHPLVLKTNFEEEEEVDEQNDASSLWTKTPEEIEEKRAIKEMCYKSGEYYRFHTPPDILSSKSMTPTAEKQLEKPLENGSELQEGDSLTVPTKLSQYERQGEIKTSLHGKPKTDIAAFENGGGDCYVPQRVIFLGVDESEALTEEKEITISKCSNTKDNKDSPHPKHSLTTRLVPTTHVLNATENISMKCREDPSSMNDVQPVKKPHFKGVKKRKWIYDEPQNFPNSGMQRAVQAPRPQNKMSYHRNNKNRNAENASYIHVQRDAVRTVALNAPSRSRPTHGSYNKVHANREPKPNLSPDKYTSTSYNDSAWRKRIPFSKTYSKSEKIYPEPRRNGSK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MEMQQNCSISCFWET CCCCCCCEEEEEEEC	25.70	24043423
10	Phosphorylation	MQQNCSISCFWETQP CCCCCEEEEEEECCC	6.23	24043423
15	Phosphorylation	SISCFWETQPLGCVK EEEEEEECCCCCEEE	26.53	24043423
120	Phosphorylation	RAIKEMCYKSGEYYR HHHHHHHHHCCCEEE	13.59	28387310
126	Phosphorylation	CYKSGEYYRFHTPPD HHHCCCEEEECCCHH	11.51	28387310
182	Phosphorylation	RQGEIKTSLHGKPKT HCCCCCCCCCCCCCC	17.23	24719451
238	Phosphorylation	NTKDNKDSPHPKHSL CCCCCCCCCCCCCCH	27.07	22210691
244	Phosphorylation	DSPHPKHSLTTRLVP CCCCCCCCHHHEEEE	33.27	22210691
246	Phosphorylation	PHPKHSLTTRLVPTT CCCCCCHHHEEEEEH	16.94	-
247	Phosphorylation	HPKHSLTTRLVPTTH CCCCCHHHEEEEEHH	27.57	-
271	Phosphorylation	MKCREDPSSMNDVQP CHHCCCCCCCCCCCC	55.32	18452278
272	Phosphorylation	KCREDPSSMNDVQPV HHCCCCCCCCCCCCC	27.30	18452278
351	Phosphorylation	TVALNAPSRSRPTHG EEEECCCCCCCCCCC	40.24	25072903
353	Phosphorylation	ALNAPSRSRPTHGSY EECCCCCCCCCCCCC	47.12	25072903
356	Phosphorylation	APSRSRPTHGSYNKV CCCCCCCCCCCCCCC	37.45	29978859
359	Phosphorylation	RSRPTHGSYNKVHAN CCCCCCCCCCCCCCC	20.23	29978859
360	Phosphorylation	SRPTHGSYNKVHANR CCCCCCCCCCCCCCC	24.48	29978859
380	Phosphorylation	LSPDKYTSTSYNDSA CCCCCCCCCCCCCHH	16.56	21130716

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CL050_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CL050_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CL050_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
G3PT_HUMAN	GAPDHS	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.