dbPTM

CKLF3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CKLF3_MOUSE
UniProt AC	Q99LJ5
Protein Name	CKLF-like MARVEL transmembrane domain-containing protein 3
Gene Name	Cmtm3
Organism	Mus musculus (Mouse).
Sequence Length	184
Subcellular Localization	Membrane Multi-pass membrane protein.
Protein Description
Protein Sequence	MWPPDAEPEPDPESAHGPRSGRTVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYVVSSASAFLTVPLLEFLLAVYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFVISITAVAKYSDGAYKAAGVFGFFATIVFAIDFYLIFNEVAKFLKQGDSGNETTAHRTEEENSNSDSDSD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	EPEPDPESAHGPRSG CCCCCCCCCCCCCCC	30.84	25338131
38	S-palmitoylation	LPARAFLCSLKGRLL HHHHHHHHHHHHHHH	3.46	28680068
163	Phosphorylation	KFLKQGDSGNETTAH HHHHCCCCCCCCCCC	50.79	23375375
168	Phosphorylation	GDSGNETTAHRTEEE CCCCCCCCCCCCCCC	17.81	27087446
172	Phosphorylation	NETTAHRTEEENSNS CCCCCCCCCCCCCCC	37.57	23684622
177	Phosphorylation	HRTEEENSNSDSDSD CCCCCCCCCCCCCCC	40.78	23375375
179	Phosphorylation	TEEENSNSDSDSD-- CCCCCCCCCCCCC--	38.01	23375375
181	Phosphorylation	EENSNSDSDSD---- CCCCCCCCCCC----	38.54	23684622
183	Phosphorylation	NSNSDSDSD------ CCCCCCCCC------	49.53	23684622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CKLF3_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CKLF3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CKLF3_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
BLNK_MOUSE	Blnk	physical	15087455

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CKLF3_MOUSE

Related Literatures of Post-Translational Modification