CKL1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CKL1_ARATH
• UniProt AC: P42158
• Protein Name: Casein kinase 1-like protein 1 {ECO:0000305}
• Gene Name: CKL1 {ECO:0000303|PubMed:16126836}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 450
• Subcellular Localization: Cytoplasm . Cell junction, plasmodesma . Present in punctate particles with granular structure.
• Protein Description: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins..
• Protein Sequence: MEPRVGNKFRLGRKIGSGSFGEIYLGTNIHTNEELAIKLENVKTKHPQLLYESKLYRILQGGTGVPNVKWFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKSVLMLADQMINRVEFFHSKSFLHRDLKPDNFLMGLGRRANQVYIIDFGLAKKYRDSTTHQHIPYRENKNLTGTARYASMNTHLGIEQSRRDDLESLGYILMYFLKGSLPWQGLKAGTKKQKYERISEKKVSTSIEALCRGYPSEFASYFHYCRSLRFDDKPDYAYLKRIFRDLFIREGFQFDYVFDWTILKYQQSQLTAPPSRALNPAVGTSAALPPGISNIDRYTGEEEGRPHMESSRRRVSGALDNSGNISNQPTSSSARDSMIPSSSLFAQSAGSSRRVTAVSGSRDNFPGSEELLQRSRTGDVSRGVIPRNSPGEAGKSTRRHYESVVKGIDNLQVSDEHHPH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
346	Phosphorylation	ESSRRRVSGALDNSG HHHHHHHHHCCCCCC		30291188
352	Phosphorylation	VSGALDNSGNISNQP HHHCCCCCCCCCCCC		25561503
361	Phosphorylation	NISNQPTSSSARDSM CCCCCCCCCCHHHHC		25561503
362	Phosphorylation	ISNQPTSSSARDSMI CCCCCCCCCHHHHCC		25561503
363	Phosphorylation	SNQPTSSSARDSMIP CCCCCCCCHHHHCCC		25561503
381	Phosphorylation	LFAQSAGSSRRVTAV HHHHHCCCCCCEEEE		25561503
382	Phosphorylation	FAQSAGSSRRVTAVS HHHHCCCCCCEEEEC		25561503
389	Phosphorylation	SRRVTAVSGSRDNFP CCCEEEECCCCCCCC		22631563
391	Phosphorylation	RVTAVSGSRDNFPGS CEEEECCCCCCCCCC		22631563
426	Phosphorylation	SPGEAGKSTRRHYES CCCCCCHHHHHHHHH		25561503
427	Phosphorylation	PGEAGKSTRRHYESV CCCCCHHHHHHHHHH		25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CKL1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CKL1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CKL1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HAT14_ARATH	HAT14	physical	21798944
1A15_ARATH	ACS5	physical	25464840

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.