CHUR_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CHUR_HUMAN
• UniProt AC: Q8WUH1
• Protein Name: Protein Churchill
• Gene Name: CHURC1
• Organism: Homo sapiens (Human).
• Sequence Length: 139
• Protein Description: Transcriptional activator that mediates FGF signaling during neural development. Plays a role in the regulation of cell movement (By similarity). Does not bind DNA by itself..
• Protein Sequence: MRQPYLSSREVSSSRKRWRTFPVDCVAMCGDCVEKEYPNRGNTCLENGSFLLNFTGCAVCSKRDFMLITNKSLKEEDGEEIVTYDHLCKNCHHVIARHEYTFSIMDEFQEYTMLCLLCGKAEDTISILPDDPRQMTLLF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
74	Sumoylation	LITNKSLKEEDGEEI EEECCCCCCCCCCEE	14.12	-
74	Sumoylation	LITNKSLKEEDGEEI EEECCCCCCCCCCEE	14.12	-
74	Ubiquitination	LITNKSLKEEDGEEI EEECCCCCCCCCCEE	14.12	-
100 (in isoform 2)	Phosphorylation	-	5.98	21406692
124	Phosphorylation	LCGKAEDTISILPDD HCCCCCHHEEECCCC		21406692
126	Phosphorylation	GKAEDTISILPDDPR CCCCHHEEECCCCHH		21406692

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CHUR_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CHUR_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CHUR_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZBTB9_HUMAN	ZBTB9	physical	20211142
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.