CG031_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CG031_HUMAN
• UniProt AC: Q8N865
• Protein Name: Uncharacterized protein C7orf31
• Gene Name: C7orf31
• Organism: Homo sapiens (Human).
• Sequence Length: 590
• Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
• Protein Sequence: MEVIHGRPYCCRELEGADILSNTFYSNELHNPLQTVTRPTASEDRYQELRESLQQCRLPWGAEREYGGIIPISLPEDHRPKYEPPRVMGKGHQHYGFGGETWPRKLPVEQFYYLTQNKKSDVYGNDSLIPKPPNSTVGEICLPYPIEHPYHTHICRGAMFPTFTSPEDLYTGIKARTQQPFPPTVPTKAYDSTVLKTRGNPYRYELIDIPMDSKKKALTWPGQGVYYDFPRGVEKNKPVFYPKPPKTFAPNTSLNSWDPICSAKEANIQRNLERSHWLTSYTHDFTGLGPMDPLELDDYHEKMVAELTRKIGFDPEPQEKFHPVFKPPRPLEGRIARLIQNRRSLEAIVQQRPRSCPDCTPRVLCNFHTFVPSSKEMVALSDNIPAGVTHKNQDIEEKIIEEQSLLSTYELPSCYPTKDLTSIYDIKPFPKITDTKKTEDLYWRQQSLKTQPTPYCKPDHWIHYENLKSPLRDQYNMCPDPVSLSKPSVLQNKQDTEAFTLEHFLSKPEEELFLNMENNEETRPVLGWIPRAGVTKPQTNLLELKNSFSKTGAQKRFHKSILEDHKDLRDNEHSGMKHQFYGHNSYYFYN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
81	Acetylation	LPEDHRPKYEPPRVM CCCCCCCCCCCCCCC	63.30	25038526
187	Phosphorylation	PFPPTVPTKAYDSTV CCCCCCCCCCCCCCE	24.78	-
192	Phosphorylation	VPTKAYDSTVLKTRG CCCCCCCCCEEECCC	14.03	30622161
193	Phosphorylation	PTKAYDSTVLKTRGN CCCCCCCCEEECCCC	27.28	30622161
196	Ubiquitination	AYDSTVLKTRGNPYR CCCCCEEECCCCCCE	31.66	-
219	Phosphorylation	DSKKKALTWPGQGVY CCCCCCCCCCCCCCE	34.18	-
252	Phosphorylation	PKTFAPNTSLNSWDP CCCCCCCCCCCCCCC	33.27	30622161
253	Phosphorylation	KTFAPNTSLNSWDPI CCCCCCCCCCCCCCC	31.99	30622161
256	Phosphorylation	APNTSLNSWDPICSA CCCCCCCCCCCCCCH	37.84	30622161
264	Acetylation	WDPICSAKEANIQRN CCCCCCHHHHHHHHH	40.86	25038526
344	Phosphorylation	RLIQNRRSLEAIVQQ HHHHCHHHHHHHHHC	27.59	24719451
373	Phosphorylation	NFHTFVPSSKEMVAL ECEEECCCCHHHHEE	49.06	30622161
374	Phosphorylation	FHTFVPSSKEMVALS CEEECCCCHHHHEEC	26.94	30622161
375	Acetylation	HTFVPSSKEMVALSD EEECCCCHHHHEECC	54.92	25038526
404	Phosphorylation	EKIIEEQSLLSTYEL HHHHHHHHHHHHCCC	34.26	30622161
407	Phosphorylation	IEEQSLLSTYELPSC HHHHHHHHHCCCCCC	33.95	30622161
408	Phosphorylation	EEQSLLSTYELPSCY HHHHHHHHCCCCCCC	22.45	30622161
413	Phosphorylation	LSTYELPSCYPTKDL HHHCCCCCCCCCCCC	38.62	19690332
421	Phosphorylation	CYPTKDLTSIYDIKP CCCCCCCCCCCCCCC	24.18	30622161
422	Phosphorylation	YPTKDLTSIYDIKPF CCCCCCCCCCCCCCC	26.84	30622161
427	Sumoylation	LTSIYDIKPFPKITD CCCCCCCCCCCCCCC	37.39	28112733
442	Phosphorylation	TKKTEDLYWRQQSLK CCCCHHCHHHHHHCC	15.74	-
483	Phosphorylation	NMCPDPVSLSKPSVL CCCCCCCCCCCHHHH	32.11	25693802
485	Phosphorylation	CPDPVSLSKPSVLQN CCCCCCCCCHHHHCC	34.71	25693802
488	Phosphorylation	PVSLSKPSVLQNKQD CCCCCCHHHHCCCCC	38.91	25693802
545	Sumoylation	QTNLLELKNSFSKTG CCCHHHHHHHHHHHC	40.96	28112733
547	Phosphorylation	NLLELKNSFSKTGAQ CHHHHHHHHHHHCHH	29.34	24719451
549	Phosphorylation	LELKNSFSKTGAQKR HHHHHHHHHHCHHHH	29.18	25693802
560	Phosphorylation	AQKRFHKSILEDHKD HHHHHHHHHHHHCCH	24.68	30622161

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CG031_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CG031_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CG031_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
PGK2_HUMAN	PGK2	physical	28514442
GRK6_HUMAN	GRK6	physical	28514442
GUAD_HUMAN	GDA	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.