CFTSY_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CFTSY_ARATH
• UniProt AC: O80842
• Protein Name: Cell division protein FtsY homolog, chloroplastic
• Gene Name: CPFTSY
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 366
• Subcellular Localization: Plastid, chloroplast stroma. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. The membrane-binding domain is capable of partial insertion into the lipid bilayer.
• Protein Description: Signal recognition particle receptor protein. Binds GTP specifically. The GTPase activity is inhibited by the N-terminus of the protein until binding to the thylakoid membrane. Activates the GTPase activity of FFC/cpSRP54 when bound to the cpSRP complex. Required for light-harvesting chlorophyll a/b-binding protein (LHCP) integration into thylakoids. Might be also functionally linked to the Sec translocation machinery..
• Protein Sequence: MATSSAHLSFLAGRISPFSSERIGLFPLRGEFRPRMTRFRCSAGPSGFFTRLGRLIKEKAKSDVEKVFSGFSKTRENLAVIDELLLFWNLAETDRVLDELEEALLVSDFGPKITVRIVERLREDIMSGKLKSGSEIKDALKESVLEMLAKKNSKTELQLGFRKPAVIMIVGVNGGGKTTSLGKLAHRLKNEGTKVLMAAGDTFRAAASDQLEIWAERTGCEIVVAEGDKAKAATVLSKAVKRGKEEGYDVVLCDTSGRLHTNYSLMEELIACKKAVGKIVSGAPNEILLVLDGNTGLNMLPQAREFNEVVGITGLILTKLDGSARGGCVVSVVEELGIPVKFIGVGEAVEDLQPFDPEAFVNAIFS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
132	Phosphorylation	IMSGKLKSGSEIKDA HHCCCCCCHHHHHHH	58.97	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CFTSY_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CFTSY_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CFTSY_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CDC23_ARATH	APC8	physical	21798944
ALB3_ARATH	ALB3	physical	20729200
SR54C_ARATH	CPSRP54	physical	21780778

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.